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[Brugada波拟表型]

[Brugada phenocopy].

作者信息

Tomcsányi János

机构信息

Kardiológia, Budai Irgalmasrendi Kórház Budapest, Árpád fejedelem u. 7. II. em., 1023.

出版信息

Orv Hetil. 2016 Mar 27;157(13):495-9. doi: 10.1556/650.2016.30385.

Abstract

Brugada phenocopies are clinical entities that are different from the true Brugada syndrome which is a channelopathy. Brugada phenocopy has reversible underlying conditions and, if underlying conditions resolve, the ECG pattern disappears. In this paper the author reviews and illustrates the known Brugada phenocopies. The most important etiologic categories of Brugada phenocopy include metabolic abnormalities (most commonly hyperkalemia), myocardial infarction, pulmonary embolism (massive), right ventricular mechanical compression, and others. The most important clinical issue is the different treatment of the Brugada syndrome and phenocopies in order to prevent cardiac death. In Brugada syndrome the implantable cardioverter defibrillator is the only effective treatment, while in Brugada phenocopies early, etiology-specific treatment can prevent cardiac death.

摘要

Brugada综合征拟表型是与真正的Brugada综合征(一种离子通道病)不同的临床实体。Brugada综合征拟表型有可逆的潜在病因,若潜在病因消除,心电图模式便会消失。在本文中,作者回顾并阐述了已知的Brugada综合征拟表型。Brugada综合征拟表型最重要的病因类别包括代谢异常(最常见的是高钾血症)、心肌梗死、肺栓塞(大面积)、右心室机械性受压等。最重要的临床问题是Brugada综合征和拟表型的治疗方式不同,以便预防心源性死亡。在Brugada综合征中,植入式心脏复律除颤器是唯一有效的治疗方法,而在Brugada综合征拟表型中,早期针对病因的治疗可预防心源性死亡。

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