Zhou Tao, Li Chuyu, Zhao Wene, Wang Xinru, Wang Fuqiang, Sha Jiahao
State Key Laboratory of Reproductive Medicine, Nanjing Medical University, Nanjing, 210029, PR China.
Analytical and Testing Center, Nanjing Medical University, Nanjing, 210029, PR China.
PLoS One. 2016 Mar 22;11(3):e0152067. doi: 10.1371/journal.pone.0152067. eCollection 2016.
MaxQuant is a proteomic software widely used for large-scale tandem mass spectrometry data. We have designed and developed an enhanced result reporting tool for MaxQuant, named as MaxReport. This tool can optimize the results of MaxQuant and provide additional functions for result interpretation. MaxReport can generate report tables for protein N-terminal modifications. It also supports isobaric labelling based relative quantification at the protein, peptide or site level. To obtain an overview of the results, MaxReport performs general descriptive statistical analyses for both identification and quantification results. The output results of MaxReport are well organized and therefore helpful for proteomic users to better understand and share their data. The script of MaxReport, which is freely available at http://websdoor.net/bioinfo/maxreport/, is developed using Python code and is compatible across multiple systems including Windows and Linux.
MaxQuant是一款广泛用于大规模串联质谱数据的蛋白质组学软件。我们为MaxQuant设计并开发了一种增强的结果报告工具,名为MaxReport。该工具可以优化MaxQuant的结果,并为结果解读提供额外功能。MaxReport可以生成蛋白质N端修饰的报告表格。它还支持在蛋白质、肽段或位点水平进行基于等压标记的相对定量。为了获得结果的概述,MaxReport对鉴定和定量结果进行一般描述性统计分析。MaxReport的输出结果组织良好,因此有助于蛋白质组学用户更好地理解和共享他们的数据。MaxReport的脚本可在http://websdoor.net/bioinfo/maxreport/免费获取,它是使用Python代码开发的,并且在包括Windows和Linux在内的多个系统上兼容。