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腹腔镜结直肠手术及加速康复外科计划中局部伤口浸润联合腹横肌平面(TAP)阻滞与局部伤口浸润的比较

Local wound infiltration plus transversus abdominis plane (TAP) block versus local wound infiltration in laparoscopic colorectal surgery and ERAS program.

作者信息

Pedrazzani Corrado, Menestrina Nicola, Moro Margherita, Brazzo Gianluca, Mantovani Guido, Polati Enrico, Guglielmi Alfredo

机构信息

Division of General and Hepatobiliary Surgery, Department of Surgery, University of Verona Hospital Trust, University of Verona, Verona, Italy.

Division of Anesthesiology, Department of Surgery, University of Verona Hospital Trust, University of Verona, Verona, Italy.

出版信息

Surg Endosc. 2016 Nov;30(11):5117-5125. doi: 10.1007/s00464-016-4862-5. Epub 2016 Mar 22.

Abstract

BACKGROUND

Few data are available on TAP block in laparoscopic colorectal surgery and ERAS program. The aim of this prospective study was to evaluate local wound infiltration plus TAP block compared to local wound infiltration in the management of postoperative pain, nausea and vomiting, ileus and use of opioids in the context of laparoscopic colorectal surgery and ERAS program.

METHODS

From March 2014 to March 2015, 48 patients were treated by laparoscopic resection and ERAS program for colorectal cancer and diverticular disease at the Division of General and Hepatobiliary Surgery, University of Verona Hospital Trust. Among these, 24 patients received local wound infiltration plus TAP block (TAP block group) and 24 patients received local wound infiltration (control group).

RESULTS

No differences were observed in baseline patient characteristics, clinical variables and surgical procedures between the two groups. Local wound infiltration plus TAP block allowed to achieve pain control despite a reduced use of opioid analgesics (P = 0.009). The adoption of TAP block resulted beneficial on the prevention of postoperative nausea (P = 0.002) and improvement of essential outcomes of ERAS program as recovery of bowel function (P = 0.005), urinary catheter removal (P = 0.003) and capability to tolerate oral diet (P = 0.027).

CONCLUSIONS

TAP block plus local wound infiltration in the setting of laparoscopic colorectal surgery and ERAS program guarantees a reduced use of opioid analgesics and good pain control allowing the improvement of essential items of enhanced recovery pathways.

摘要

背景

关于腹腔镜结直肠手术及加速康复外科(ERAS)方案中腹横肌平面(TAP)阻滞的数据较少。本前瞻性研究的目的是评估在腹腔镜结直肠手术及ERAS方案中,局部伤口浸润联合TAP阻滞与单纯局部伤口浸润相比,在术后疼痛、恶心呕吐、肠梗阻及阿片类药物使用管理方面的效果。

方法

2014年3月至2015年3月,维罗纳大学医院信托普通与肝胆外科对48例因结直肠癌和憩室病接受腹腔镜切除术及ERAS方案治疗的患者进行了研究。其中,24例患者接受局部伤口浸润联合TAP阻滞(TAP阻滞组),24例患者接受局部伤口浸润(对照组)。

结果

两组患者的基线特征、临床变量和手术操作均无差异。局部伤口浸润联合TAP阻滞在减少阿片类镇痛药使用的情况下仍能实现疼痛控制(P = 0.009)。采用TAP阻滞对预防术后恶心(P = 0.002)以及改善ERAS方案的关键指标如肠功能恢复(P = 0.005)、拔除导尿管(P = 0.003)和耐受口服饮食的能力(P = 0.027)均有有益作用。

结论

在腹腔镜结直肠手术及ERAS方案中,TAP阻滞联合局部伤口浸润可减少阿片类镇痛药的使用并实现良好的疼痛控制,从而改善加速康复路径的关键指标。

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