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强直性脊柱炎与骨关节炎患者全髋关节置换术后失血情况的比较。

Comparison of Blood Loss After Total Hip Arthroplasty Between Ankylosing Spondylitis and Osteoarthritis.

作者信息

Li Jia, Zhao Jinzhu, He Chongru, Tong Wenwen, Zou Yuming, Xu Weidong

机构信息

Department of Orthopedics, Changhai Hospital Affiliated to the Second Military Medical University, Shanghai, China.

Department of Orthopedics, No. 401 Hospital, Jinan Military Region of PLA, Qingdao, Shandong, China.

出版信息

J Arthroplasty. 2016 Jul;31(7):1504-9. doi: 10.1016/j.arth.2015.12.049. Epub 2016 Feb 27.

Abstract

BACKGROUND

This study was conducted to compare the blood loss during primary total hip arthroplasty (THA) between ankylosing spondylitis (AS) and hip osteoarthritis (OA).

METHODS

We reviewed 120 THAs in 68 patients comprising 3 groups: AS with total bony ankylosis of the hips (ASB), AS with stiff hips (ASS), and OA. Demographics, perioperative laboratory values, intraoperative data, blood loss, transfusion rate, transfusion reactions, surgical complications, hospitalization cost, and length of stay (LOS) were collected and analyzed among ASB, ASS, and OA groups.

RESULTS

The patients of the ASB and ASS groups were much younger and thinner than those of the OA group. There were no significant differences in the preoperative values of activated partial thromboplastin time, prothrombin time, and international normalized ratio among the 3 groups (all P > .05). The intraoperative blood loss, volume of drainage, hidden blood loss, transfusion rate, transfusion reactions, and hospitalization cost in the ASB group were significantly higher than in the other 2 groups, although not significantly different between the ASS and OA groups (P > .05).

CONCLUSION

Both AS and OA can cause hyperosteogeny to the hips, but ASB patients have more serious symptoms in their affected hips. This may cause more blood loss in THA surgery because of bone surface bleeding. The reason that ASB patients suffered more blood loss may be related to the high difficulty and long duration of the operation.

摘要

背景

本研究旨在比较强直性脊柱炎(AS)和髋关节骨关节炎(OA)患者初次全髋关节置换术(THA)期间的失血量。

方法

我们回顾了68例患者的120例THA手术,分为3组:髋关节完全骨性强直的AS患者(ASB)、髋关节僵硬的AS患者(ASS)和OA患者。收集并分析了ASB组、ASS组和OA组患者的人口统计学资料、围手术期实验室检查值、术中数据、失血量、输血率、输血反应、手术并发症、住院费用和住院时间(LOS)。

结果

ASB组和ASS组患者比OA组患者更年轻、体重更轻。3组患者术前活化部分凝血活酶时间、凝血酶原时间和国际标准化比值无显著差异(均P>.05)。ASB组术中失血量、引流量、隐性失血量、输血率、输血反应和住院费用均显著高于其他2组,而ASS组和OA组之间无显著差异(P>.05)。

结论

AS和OA均可导致髋关节骨质增生,但ASB患者患侧髋关节症状更严重。这可能导致THA手术中因骨面出血而失血更多。ASB患者失血更多的原因可能与手术难度大、时间长有关。

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