Nan Jiangyu, Chen Hengxin, Qian Hu, Lei Ting, Hu Yihe
Department of Orthopedic Surgery, The First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
Department of Urology, Liuzhou Traditional Chinese Medical Hospital, Liuzhou, China.
BMC Musculoskelet Disord. 2025 May 19;26(1):496. doi: 10.1186/s12891-025-08752-3.
Total hip arthroplasty (THA) has been applied as a successful treatment for repairing the impaired hip joints of patients with advanced inflammatory arthritis. Few studies compared the inpatient clinical characteristics of these patients receiving THA due to inflammatory arthritis. This study aims to compare the perioperative clinical outcome of patients receiving THA due to rheumatoid arthritis (RA) or ankylosing spondylitis (AS).
We retrospectively included 60 patients receiving THA due to RA or AS, and compared their inpatient clinical characteristics. The collected data comprised baseline data including gender, age, body mass index (BMI), blood pressure, Barthel index and clinical outcomes including operative time, perioperative blood loss, perioperative inflammatory indicators, length of hospitalization, inpatient medicine cost and perioperative complications.
AS patients showed increased operative blood loss and autologous transfusion rate than the RA patients. In addition, RA patients showed increased serum level of erythrocyte sedimentation rate (ESR) and interleukin-6 (IL-6), while no significant difference was found between the two groups in length of hospitalization, medicine cost and perioperative complications.
We suggested that more attention should be paid to the blood loss management of AS patients during perioperative stage, since AS patients were more susceptible to blood loss during THA with the potential reason to remove large amounts of osteophyte.
全髋关节置换术(THA)已被用作修复晚期炎症性关节炎患者受损髋关节的一种成功治疗方法。很少有研究比较因炎症性关节炎接受THA治疗的这些患者的住院临床特征。本研究旨在比较类风湿关节炎(RA)或强直性脊柱炎(AS)患者接受THA治疗的围手术期临床结局。
我们回顾性纳入了60例因RA或AS接受THA治疗的患者,并比较了他们的住院临床特征。收集的数据包括基线数据,如性别、年龄、体重指数(BMI)、血压、巴氏指数,以及临床结局,如手术时间、围手术期失血量、围手术期炎症指标、住院时间、住院药费和围手术期并发症。
AS患者的手术失血量和自体输血率高于RA患者。此外,RA患者的红细胞沉降率(ESR)和白细胞介素-6(IL-6)血清水平升高,而两组在住院时间、药费和围手术期并发症方面未发现显著差异。
我们建议在围手术期应更加关注AS患者的失血管理,因为AS患者在THA手术期间更容易失血,潜在原因是要去除大量骨赘。