Lee Robert C, Darling Cynthia L, Fried Daniel
University of California, San Francisco, San Francisco, CA 94143-0758.
Proc SPIE Int Soc Opt Eng. 2016 Feb 13;9692. doi: 10.1117/12.2218661. Epub 2016 Feb 29.
Accurate detection and measurement of the highly mineralized surface layer that forms on caries lesions is important for the diagnosis of lesion activity. Previous studies have demonstrated that optical imaging methods can be used to measure the degree of remineralization on enamel lesions. The purpose of this study was to determine if thermal and near-IR reflectance imaging could be used to assess the remineralization process in simulated dentin lesions. Artificial bovine (n=15) dentin lesions were prepared by immersion in a demineralization solution for 24 hours and they were subsequently placed in an acidic remineralization solution for up to 12 days. The samples were dehydrated using an air spray for 30 seconds and imaged using thermal and InGaAs cameras. The area enclosed by the time-temperature curve, ΔQ, from thermal imaging decreased significantly with longer periods of remineralization. However, near-IR reflectance intensity differences, ΔI, before and after dehydration failed to show any significant relationship with the degree of remineralization. This study shows that thermal imaging can be used for the assessment of the remineralization of dentin lesions.
准确检测和测量龋损表面形成的高度矿化层对于病变活动的诊断至关重要。先前的研究表明,光学成像方法可用于测量釉质龋损的再矿化程度。本研究的目的是确定热反射成像和近红外反射成像是否可用于评估模拟牙本质龋损的再矿化过程。通过将人工牛(n = 15)牙本质样本浸泡在脱矿溶液中24小时来制备龋损,随后将其置于酸性再矿化溶液中长达12天。使用空气喷雾将样本脱水30秒,并使用热成像相机和铟镓砷相机进行成像。热成像中,随再矿化时间延长,时间-温度曲线所围面积ΔQ显著减小。然而,脱水前后的近红外反射强度差异ΔI与再矿化程度未显示出任何显著关系。本研究表明,热成像可用于评估牙本质龋损的再矿化情况。