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胎儿无创心电图的应用

The Use of Fetal Noninvasive Electrocardiography.

作者信息

Lakhno Igor

机构信息

Perinatology, Obstetrics and Gynecology Department, Kharkiv Medical Academy of Postgraduate Education, 58 Shalimov Street, Kharkiv 61176, Ukraine.

出版信息

Scientifica (Cairo). 2016;2016:5386595. doi: 10.1155/2016/5386595. Epub 2016 Feb 24.

Abstract

Preeclampsia (PE) is one of the severe complications of pregnancy that leads to fetal deterioration. The aim was to survey the validity of fetal distress diagnostics in case of Doppler ultrasonic umbilical vein and arteries blood flow velocity investigation and ECG parameters analysis obtained from maternal abdominal signal before labor in preeclamptic patients. Fetal noninvasive ECG and umbilical arterial and venous Doppler investigation were performed in 120 patients at 34-40 weeks of gestation. And 30 of them had physiological gestation and were involved in Group I. In Group II 52 pregnant women with mild-moderate PE were observed. 38 patients with severe PE were monitored in Group III. The most considerable negative correlation was determined in pair Apgar score 1 versus T/QRS (R = -0.50; p < 0.05). So the increased T/QRS ratio was the most evident marker of fetal distress. Fetal noninvasive ECG showed sensitivity of 96.6% and specificity of 98.4% and, therefore, was determined as more accurate method for fetal monitoring.

摘要

子痫前期(PE)是导致胎儿状况恶化的严重妊娠并发症之一。目的是在子痫前期患者分娩前,通过对多普勒超声脐静脉和动脉血流速度进行调查以及对从母体腹部信号获得的心电图参数进行分析,来评估胎儿窘迫诊断的有效性。对120例妊娠34 - 40周的患者进行了胎儿无创心电图以及脐动脉和静脉多普勒检查。其中30例为生理妊娠,归入第一组。第二组观察了52例轻度至中度子痫前期的孕妇。第三组监测了38例重度子痫前期患者。在Apgar评分1与T/QRS的配对中确定了最显著的负相关(R = -0.50;p < 0.05)。因此,T/QRS比值升高是胎儿窘迫最明显的标志。胎儿无创心电图显示敏感性为96.6%,特异性为98.4%,因此被确定为更准确的胎儿监测方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c7f4/4783547/e9717ec18dff/SCIENTIFICA2016-5386595.001.jpg

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