Department of Obstetrics and Gynecology, Pomeranian Medical University, Szczecin, Poland.
Ann Acad Med Singap. 2010 Jan;39(1):27-32.
The aim of the study was to review clinical and laboratory outcomes of a cohort of fetuses monitored during high-risk labours, simultaneously by fetal electrocardiography (FECG) and routine cardiotocography (CTG).
Eighty-three parturients from the Department of Obstetrics and Gynecology of Medical University were included in the clinical study. Inclusive criteria to the study group were: (i) singleton pregnancy at term (between 37 and 42 weeks' gestation), (ii) longitudinal fetal lying, (iii) more than 2500 g of estimated fetal weight, (iv) meconium-stained liquor, and (v) induction of labour due to fetal indications. Fetal outcome parameters analysed included Apgar scores at 1st, 5th and 10th minute after birth, cord artery acid-base assessment and lactate concentrations analysis. FECG was performed during labour, until the neonate was born, with the use of single spiral scalp electrode connected to the STAN S21 heart monitor. Immediately after delivery, arterial cord blood gas and venous cord blood lactate's concentrations were analysed.
The sensitivity (100%), specificity (97%), negative predictive value (NPV) (100%) and positive predictive value (33%) were higher for FECG than for CTG. Moreover, several significant correlations between episodic/baseline T/QRS ratio rises and cord artery acid-base as well as lactate concentrations were demonstrated.
Correlations between episodic/baseline T/QRS ratio rises and fetal outcome parameters indicate that observed changes in FECG reflect neonatal metabolic lactate acidosis. The high sensitivity, specificity and especially very high NPV are proof that FECG serves as a reliable method for electronic fetal monitoring during high-risk labours.
本研究旨在回顾同时通过胎儿心电图(FECG)和常规胎心监护(CTG)监测高危分娩胎儿的临床和实验室结果。
该临床研究纳入了来自医科大学妇产科的 83 名产妇。纳入研究组的标准为:(i)单胎妊娠足月(37 至 42 周),(ii)纵向胎儿卧位,(iii)估计胎儿体重超过 2500 克,(iv)胎粪污染羊水,以及(v)因胎儿指征引产。分析的胎儿结局参数包括出生后 1 分钟、5 分钟和 10 分钟的 Apgar 评分、脐动脉酸碱评估和乳酸浓度分析。在分娩期间使用单螺旋头皮电极连接到 STAN S21 心脏监护仪进行 FECG,直至新生儿出生。分娩后立即分析脐动脉血气和脐静脉血乳酸浓度。
FECG 的敏感性(100%)、特异性(97%)、阴性预测值(NPV)(100%)和阳性预测值(33%)均高于 CTG。此外,还证明了间歇性/基线 T/QRS 比值升高与脐动脉酸碱值和乳酸浓度之间存在一些显著相关性。
间歇性/基线 T/QRS 比值升高与胎儿结局参数之间的相关性表明,FECG 观察到的变化反映了新生儿代谢性乳酸酸中毒。高敏感性、特异性,特别是非常高的 NPV 证明 FECG 是高危分娩中电子胎儿监测的可靠方法。