Sergi Bruno, Lucidi Daniela, De Corso Eugenio, Paludetti Gaetano
Department of Head and Neck Surgery, Institute of Otorhinolaryngology, Catholic University School of Medicine and Surgery, "A. Gemelli" Hospital, Largo A. Gemelli n.1, 00168, Rome, Italy.
Eur Arch Otorhinolaryngol. 2016 Nov;273(11):3623-3629. doi: 10.1007/s00405-016-3976-7. Epub 2016 Mar 23.
The use of "one-shot" CO laser technique for a primary small-fenestra stapedotomy is well established, but few papers report the long-term functional results. We retrospectively reviewed medical records of 198 patients, treated for otosclerosis from January 2008 to December 2011, at the Department of Head and Neck Surgery, Catholic University of Rome. Statistical comparison between audiological thresholds obtained 24 h preoperatively, at early (4 weeks) and late postoperative examinations (mean time 45 months), was performed. Comparison of preoperative vs both early and late postoperative ACPTA showed a statistically significant difference (respectively 55 vs 33 and 31 dB; p < 0.001). No statistical difference was observed between preoperative, early and late postoperative BCPTA (respectively 23 vs 23 and 22 dB; p > 0.05). Both early and late postoperative ABG improved significantly compared to the preoperative one (respectively 10 and 9 vs 32 dB; p < 0.001). No statistical difference was found in comparison of early vs late postoperative ACPTA (respectively 33 vs 31 dB; p > 0.05), early vs late postoperative ABG (respectively 10 vs 9 dB; p > 0.05) and early vs late ABG gain (respectively 22 vs 23 dB; p > 0.05). No subjects developed postoperative complications requiring revision surgery or late deterioration of hearing threshold. The analysis of our data suggests that "one-shot" CO laser stapedotomy is an effective and safe procedure: it allows a rapid stapedotomy without damages for the inner ear and optimal functional results that remain stable during the years.
“单次”CO激光技术用于原发性小开窗镫骨切除术已得到充分认可,但很少有论文报道其长期功能结果。我们回顾性分析了2008年1月至2011年12月在罗马天主教大学头颈外科接受耳硬化症治疗的198例患者的病历。对术前24小时、术后早期(4周)和晚期(平均时间45个月)获得的听力学阈值进行了统计学比较。术前与术后早期和晚期的气导纯音平均听阈(ACPTA)比较显示有统计学显著差异(分别为55 vs 33和31dB;p < 0.001)。术前、术后早期和晚期的骨导纯音平均听阈(BCPTA)之间未观察到统计学差异(分别为23 vs 23和22dB;p > 0.05)。与术前相比,术后早期和晚期的气骨导差(ABG)均有显著改善(分别为10和9 vs 32dB;p < 0.001)。术后早期与晚期的ACPTA比较(分别为33 vs 31dB;p > 0.05)、术后早期与晚期的ABG比较(分别为10 vs 9dB;p > 0.05)以及术后早期与晚期的ABG增益比较(分别为22 vs 23dB;p > 0.05)均未发现统计学差异。没有患者出现需要翻修手术的术后并发症或听力阈值的晚期恶化。我们的数据分析表明,“单次”CO激光镫骨切除术是一种有效且安全的手术:它能快速完成镫骨切除术,对内耳无损伤,并能获得多年来保持稳定的最佳功能结果。