Ahmed Shaik, Lindsay Jeanine M, Snyder Dawn I
Interventional Pain Center, Geisinger Medical Center, Danville, PA.
Interventional Pain Center, Geisinger Medical Center, Danville, PA; School of Nursing, Pennsylvania College of Technology, Williamsport, PA; Jersey Shore Hospital, Jersey Shore.
Pain Physician. 2016 Mar;19(3):E487-93.
Spinal cord stimulation (SCS) is a form of neuromodulation, used to treat chronic neuropathic pain refractory to conventional medical management. Spinal cord stimulators are treatment options when intractable chronic pain has not responded to more conventional treatment modalities. Currently, the use of SCS is contraindicated in pregnancy. Nevertheless, many SCS/neuromodulation recipients are women of child bearing age who may become pregnant. There are no published reports that focus on the possible side effects of SCS or neuromodulation therapy on human fertility, fetal development, pregnancy, delivery, or lactation.
The purpose of this current report is to present a case study on the use of SCS/neuromodulation during pregnancy.
Presentation of the case of a 24 year old female who became pregnant after receiving an SCS implantation for pain control secondary to complex regional pain syndrome (CRPS). The SCS was in use at the time of conception but deactivated when patient became aware of her pregnancy and intermittently reactivated for five minute intervals throughout the entire pregnancy.
Currently very little documented evidence is available regarding the safety of using a SCS/neuromodulator during pregnancy; therefore its use during pregnancy is contraindicated. Available literature suggests that, women who have chosen to keep the SCS/neuromodulator activated during pregnancy have delivered healthy babies without any life threatening complications.
Case presentations do not provide conclusive evidence of treatment effectiveness. This data is only preliminary and future studies should be used to assess outcomes and measures to provide quantification of the SCS implantation during pregnancy.
Women of child bearing age who are recipients of SCS/neuromodulation implantation should be informed of the limited knowledge available regarding the impact of SCS/neuromodulation use during pregnancy. For current recipients, decisions about ongoing use during pregnancy should be an individual decision based on the potential risks and benefits.
脊髓刺激(SCS)是一种神经调节形式,用于治疗对传统药物治疗无效的慢性神经性疼痛。当顽固性慢性疼痛对更传统的治疗方式无反应时,脊髓刺激器是一种治疗选择。目前,SCS在妊娠期间是禁忌的。然而,许多接受SCS/神经调节治疗的患者是育龄期女性,她们可能会怀孕。目前尚无关于SCS或神经调节疗法对人类生育、胎儿发育、妊娠、分娩或哺乳可能产生的副作用的报道。
本报告的目的是介绍一例妊娠期间使用SCS/神经调节的病例研究。
介绍一名24岁女性的病例,该女性因复杂性区域疼痛综合征(CRPS)继发疼痛接受SCS植入后怀孕。受孕时SCS正在使用,但患者意识到自己怀孕后将其停用,并在整个孕期中间歇性重新激活5分钟。
目前关于妊娠期间使用SCS/神经调节器的安全性的文献证据非常少;因此,妊娠期间禁止使用。现有文献表明,选择在妊娠期间保持SCS/神经调节器激活的女性已分娩出健康婴儿,没有任何危及生命的并发症。
病例报告不能提供治疗有效性的确凿证据。这些数据只是初步的,未来的研究应评估结果和措施,以量化妊娠期间SCS植入的情况。
接受SCS/神经调节植入的育龄期女性应被告知关于妊娠期间使用SCS/神经调节的影响的现有知识有限。对于目前的接受者,关于妊娠期间是否继续使用的决定应基于潜在风险和益处,由个人做出。