相似文献
1
Hypertension: the missing WNKs.高血压：缺失的WNKs蛋白
Am J Physiol Renal Physiol. 2016 Jul 1;311(1):F16-27. doi: 10.1152/ajprenal.00358.2015. Epub 2016 Mar 23.
2
Extrarenal roles of the with-no-lysine[K] kinases (WNKs).无赖氨酰[K]激酶（WNKs）的肾外作用。
Clin Exp Pharmacol Physiol. 2013 Dec;40(12):885-94. doi: 10.1111/1440-1681.12108.
3
WNK kinases and essential hypertension.WNK激酶与原发性高血压
Curr Opin Nephrol Hypertens. 2008 Mar;17(2):133-7. doi: 10.1097/MNH.0b013e3282f4e4fd.
4
WNKs: protein kinases with a unique kinase domain.WNK激酶：具有独特激酶结构域的蛋白激酶。
Exp Mol Med. 2007 Oct 31;39(5):565-73. doi: 10.1038/emm.2007.62.
5
The WNKs: atypical protein kinases with pleiotropic actions.WNKs：具有多种作用的非典型蛋白激酶。
Physiol Rev. 2011 Jan;91(1):177-219. doi: 10.1152/physrev.00017.2010.
6
Phosphoregulation of the Na-K-2Cl and K-Cl cotransporters by the WNK kinases.WNK激酶对钠-钾-2氯协同转运蛋白和钾-氯协同转运蛋白的磷酸化调节
Biochim Biophys Acta. 2010 Dec;1802(12):1150-8. doi: 10.1016/j.bbadis.2010.07.009. Epub 2010 Jul 15.
7
Mechanism of regulation of renal ion transport by WNK kinases.WNK激酶对肾离子转运的调节机制。
Curr Opin Nephrol Hypertens. 2008 Sep;17(5):519-25. doi: 10.1097/MNH.0b013e32830dd580.
8
Cotransporters, WNKs and hypertension: an update.协同转运蛋白、WNK激酶与高血压：最新进展
Curr Opin Nephrol Hypertens. 2008 Mar;17(2):186-92. doi: 10.1097/MNH.0b013e3282f5244e.
9
WNK kinases and the control of blood pressure.WNK激酶与血压调控
Pharmacol Ther. 2005 May;106(2):221-31. doi: 10.1016/j.pharmthera.2004.11.010. Epub 2005 Jan 26.
10
The WNK-SPAK/OSR1 pathway: master regulator of cation-chloride cotransporters.WNK-SPAK/OSR1信号通路：阳离子-氯离子共转运体的主要调节因子。
Sci Signal. 2014 Jul 15;7(334):re3. doi: 10.1126/scisignal.2005365.
引用本文的文献
1
G Protein-Coupled Receptor 35 Suppresses Oxidative Stress Responsive Kinase 1 in Diabetic Wound Healing.G蛋白偶联受体35在糖尿病伤口愈合中抑制氧化应激反应激酶1
Diabetes. 2025 Jul 1;74(7):1233-1246. doi: 10.2337/db24-0737.
2
Unanticipated domain requirements for Drosophila Wnk kinase in vivo.果蝇 Wnk 激酶体内意料之外的结构域需求。
PLoS Genet. 2023 Oct 11;19(10):e1010975. doi: 10.1371/journal.pgen.1010975. eCollection 2023 Oct.
3
Identification of a Class of WNK Isoform-Specific Inhibitors Through High-Throughput Screening.通过高通量筛选鉴定一类 WNK 同工型特异性抑制剂。
Drug Des Devel Ther. 2023 Jan 20;17:93-105. doi: 10.2147/DDDT.S389461. eCollection 2023.
4
Regulation of Distal Nephron Transport by Intracellular Chloride and Potassium.细胞内氯离子和钾离子对远曲小管转运的调节。
Nephron. 2023;147(3-4):203-211. doi: 10.1159/000526051. Epub 2022 Aug 17.
5
WNK1 in Malignant Behaviors: A Potential Target for Cancer?WNK1在恶性行为中的作用：癌症的潜在靶点？
Front Cell Dev Biol. 2022 Jun 22;10:935318. doi: 10.3389/fcell.2022.935318. eCollection 2022.
6
UBR5 is a novel regulator of WNK1 stability.UBR5 是 WNK1 稳定性的一种新型调节因子。
Am J Physiol Cell Physiol. 2022 Jun 1;322(6):C1176-C1186. doi: 10.1152/ajpcell.00417.2021. Epub 2022 Apr 20.
7
WNK3 promotes the invasiveness of glioma cell lines under hypoxia by inducing the epithelial-to-mesenchymal transition.WNK3通过诱导上皮-间质转化促进胶质瘤细胞系在缺氧条件下的侵袭能力。
Transl Neurosci. 2021 Aug 25;12(1):320-329. doi: 10.1515/tnsci-2020-0180. eCollection 2021 Jan 1.
8
Osmosensing by WNK Kinases.WNK 激酶的渗透压感知作用。
Mol Biol Cell. 2021 Aug 19;32(18):1614-1623. doi: 10.1091/mbc.E20-01-0089. Epub 2021 Mar 10.
9
WNK4 kinase is a physiological intracellular chloride sensor.WNK4 激酶是一种生理性的细胞内氯离子感受器。
Proc Natl Acad Sci U S A. 2019 Mar 5;116(10):4502-4507. doi: 10.1073/pnas.1817220116. Epub 2019 Feb 14.
10
Angiotensin II Signal Transduction: An Update on Mechanisms of Physiology and Pathophysiology.血管紧张素 II 信号转导：对生理和病理生理学机制的最新研究。
Physiol Rev. 2018 Jul 1;98(3):1627-1738. doi: 10.1152/physrev.00038.2017.
本文引用的文献
1
Regulation of Renal Electrolyte Transport by WNK and SPAK-OSR1 Kinases.WNK和SPAK-OSR1激酶对肾脏电解质转运的调节
Annu Rev Physiol. 2016;78:367-89. doi: 10.1146/annurev-physiol-021115-105431.
2
Deletion of the WNK3-SPAK kinase complex in mice improves radiographic and clinical outcomes in malignant cerebral edema after ischemic stroke.小鼠中WNK3-SPAK激酶复合物的缺失改善了缺血性中风后恶性脑水肿的影像学和临床结果。
J Cereb Blood Flow Metab. 2017 Feb;37(2):550-563. doi: 10.1177/0271678X16631561. Epub 2016 Jul 20.
3
Chronic Metabolic Acidosis Activates Renal Tubular Sodium Chloride Cotransporter through Angiotension II-dependent WNK4-SPAK Phosphorylation Pathway.慢性代谢性酸中毒通过血管紧张素II依赖的WNK4-SPAK磷酸化途径激活肾小管氯化钠协同转运蛋白。
Sci Rep. 2016 Jan 5;6:18360. doi: 10.1038/srep18360.
4
Role of epithelial Na+ channels in endothelial function.上皮钠通道在内皮功能中的作用。
J Cell Sci. 2016 Jan 15;129(2):290-7. doi: 10.1242/jcs.168831. Epub 2015 Nov 30.
5
Roles of Akt and SGK1 in the Regulation of Renal Tubular Transport.Akt和SGK1在肾小管转运调节中的作用。
Biomed Res Int. 2015;2015:971697. doi: 10.1155/2015/971697. Epub 2015 Sep 28.
6
Impaired degradation of WNK by Akt and PKA phosphorylation of KLHL3.Akt和PKA对KLHL3的磷酸化作用导致WNK降解受损。
Biochem Biophys Res Commun. 2015 Nov 13;467(2):229-34. doi: 10.1016/j.bbrc.2015.09.184. Epub 2015 Oct 3.
7
Unique chloride-sensing properties of WNK4 permit the distal nephron to modulate potassium homeostasis.WNK4独特的氯离子感知特性使远端肾单位能够调节钾稳态。
Kidney Int. 2016 Jan;89(1):127-34. doi: 10.1038/ki.2015.289. Epub 2016 Jan 4.
8
Involvement of selective autophagy mediated by p62/SQSTM1 in KLHL3-dependent WNK4 degradation.由p62/SQSTM1介导的选择性自噬参与KLHL3依赖性WNK4的降解。
Biochem J. 2015 Nov 15;472(1):33-41. doi: 10.1042/BJ20150500. Epub 2015 Sep 8.
9
Mutant Cullin causes cardiovascular compromise.突变型Cullin会导致心血管功能受损。
EMBO Mol Med. 2015 Oct;7(10):1254-6. doi: 10.15252/emmm.201505620.
10
Characterisation of the Cullin-3 mutation that causes a severe form of familial hypertension and hyperkalaemia.导致严重家族性高血压和高钾血症的Cullin-3突变的特征分析。
EMBO Mol Med. 2015 Oct;7(10):1285-306. doi: 10.15252/emmm.201505444.
Zotero 插件