Giacovazzo M, Di Sabato F, Ruggieri L, Martelletti P
Riv Eur Sci Med Farmacol. 1989 Aug;11(4):301-5.
Fourty-eight cluster headache patients have been studied. Twenty-nine of them were affected also by rhythm cardiac abnormalities, and the other 19 by associated conjunctival hyperaemia. The presence of organ-specific autoantibodies was investigated by immunofluorescence. High titers of antibodies against cardiac antigenic determinants was found. The study of leukocyte subpopulations revealed a parallel increase in blood and in conjunctival mucosa of Leu7+ and LeuM3+ cells. These outcomes confirm the immunopathological theory of cluster headache.
对48名丛集性头痛患者进行了研究。其中29名患者还伴有节律性心脏异常，另外19名伴有结膜充血。通过免疫荧光法研究了器官特异性自身抗体的存在情况。发现了针对心脏抗原决定簇的高滴度抗体。白细胞亚群的研究显示，血液和结膜黏膜中Leu7+和LeuM3+细胞平行增加。这些结果证实了丛集性头痛的免疫病理学说。
