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新生小牛脑室周围白质软化症

Periventricular leukomalacia in a neonatal calf.

作者信息

Koyama Kenji, Fujita Riku, Maezawa Masaki, Fukumoto Natsuko, Horiuchi Noriyuki, Inokuma Hisashi, Kobayashi Yoshiyasu

机构信息

Laboratory of Veterinary Pathology, Department of Basic Veterinary Medicine, Obihiro University of Agriculture and Veterinary Medicine, Nishi 2-11, Inada-cho, Obihiro, Hokkaido 080-8555, Japan.

出版信息

J Vet Med Sci. 2016 Aug 1;78(7):1175-7. doi: 10.1292/jvms.16-0034. Epub 2016 Mar 24.

Abstract

A 10-day-old, Japanese Black, female calf had shown astasia since just after birth. Focal symmetrical periventricular malacic lesions of the cerebrum and suppurative arthritis of the left hip joint were observed in macroscopic examination. Histologically, the cerebral lesions were confirmed as periventricular leukomalacia (PVL). The location and histological features of the lesions were similar to PVL in humans, caused by neonatal ischemia/hypovolemia. This is the first report of PVL in a neonatal calf.

摘要

一头10日龄的日本黑毛雌性犊牛自出生后不久就出现了站立不稳的症状。大体检查发现大脑有局灶性对称性脑室周围软化性病变以及左髋关节化脓性关节炎。组织学检查证实脑部病变为脑室周围白质软化症(PVL)。这些病变的位置和组织学特征与人类因新生儿缺血/血容量过低引起的PVL相似。这是关于新生犊牛发生PVL的首例报告。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b31/4976274/ef933e21b4cd/jvms-78-1175-g001.jpg

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