Gasiorowski W, Krzemińska T, Ostrowska W, Woy-Wojciechowski J
Endokrynol Pol. 1989;40(4):199-212.
Scintigraphic and gammagraphic (gamma-camera) techniques have been applied in diagnosing "hot" non-TSH dependent thyroid nodules. On the basis of frequent uneven accumulation of isotopic tracer observed in scintigraphic studies it was concluded that the structure of these nodules is heterogeneous. In some cases paradoxical patterns have been obtained following the dynamic tests of suppression and stimulation of the thyroid: after the administration of thyroid preparations paranodular thyroid tissue appears, while TSH administration causes an increase in the iodine uptake by the nodule. Ultrasonographic and gamma-camera studies have been carried out in 50 cases of "hot" autonomic thyroid nodules previously diagnosed by scintigraphy. Ultrasonographic studies revealed a weaker echogenicity in some cases and an intensified echo in the other. Sometimes by using this technique it was possible to demonstrate the occurrence of heterogeneous structures suggesting a cystic degeneration of the nodule. Paranodular thyroid tissue, invisible in scintigraphic scanning, could usually be observed by applying gamma-camera. It was concluded that both gamma camera and ultrasonographic studies confirm heterogeneous structure of intranodular tissue producing paradoxical patterns in scintigraphic scanning, with the latter technique usually aiding the detection of paranodular thyroid tissue without the necessity of application of the TSH test.
闪烁扫描和γ照相（γ相机）技术已被应用于诊断“热”的非促甲状腺激素依赖性甲状腺结节。基于闪烁扫描研究中观察到的同位素示踪剂频繁不均匀积聚，得出这些结节的结构是异质性的结论。在某些情况下，甲状腺抑制和刺激的动态试验后出现了矛盾的模式：给予甲状腺制剂后出现结节旁甲状腺组织，而给予促甲状腺激素会导致结节碘摄取增加。对50例先前经闪烁扫描诊断为“热”自主性甲状腺结节的患者进行了超声和γ相机研究。超声研究在某些情况下显示回声减弱，在其他情况下显示回声增强。有时使用该技术可以显示异质性结构的存在，提示结节发生囊性变。在闪烁扫描中不可见的结节旁甲状腺组织，通常应用γ相机可以观察到。得出的结论是，γ相机和超声研究均证实了结节内组织的异质性结构，在闪烁扫描中产生矛盾模式，后一种技术通常有助于检测结节旁甲状腺组织，而无需进行促甲状腺激素试验。
