与抗肿瘤坏死因子治疗相关的组织胞浆菌病垂直传播
Vertical Transmission of Histoplasmosis Associated With Anti-Tumor Necrosis Factor Therapy.
作者信息
Carlucci James G, Halasa Natasha, Creech C Buddy, Dulek Daniel E, Gómez-Duarte Oscar G, Nelson George E, Talbot H Keipp, Scalise Melissa L, Scott Patricia L, Mahadevan Uma, Beaulieu Dawn B
机构信息
Division of Pediatric Infectious Diseases, Department of Pediatrics.
Division of Infectious Diseases.
出版信息
J Pediatric Infect Dis Soc. 2016 Jun;5(2):e9-e12. doi: 10.1093/jpids/piw001. Epub 2016 Mar 24.
Abstract
Therapeutics blocking the activity of tumor necrosis factor (anti-TNF) are a risk factor for invasive fungal infections; however, infectious risks to infants born to mothers receiving anti-TNF therapy are not well defined. We report a case of vertical transmission of disseminated histoplasmosis in a mother-infant pair exposed to anti-TNF therapy.
摘要
阻断肿瘤坏死因子活性的治疗方法（抗TNF）是侵袭性真菌感染的一个危险因素；然而，接受抗TNF治疗的母亲所生婴儿的感染风险尚不清楚。我们报告了一对母婴在接受抗TNF治疗时发生播散性组织胞浆菌病垂直传播的病例。
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