Hanington E
Biomed Pharmacother. 1989;43(10):719-26. doi: 10.1016/0753-3322(89)90160-1.
The proposal that migraine is a blood disorder and caused by a primary abnormality of platelet behaviour was first put forward in 1978. This paper outlines the basis on which the proposal was made and the way in which the platelet hypothesis can account for the many facets of the disorder. It also reports further studies of platelet composition and function which have been undertaken by a large number of independent workers during the past ten years. The results of their investigations provide strong additional support for the platelet hypothesis in migraine.
偏头痛是一种血液紊乱疾病，由血小板行为的原发性异常引起，这一观点于1978年首次提出。本文概述了提出该观点的依据，以及血小板假说能够解释该疾病诸多方面的方式。本文还报告了许多独立研究人员在过去十年中对血小板组成和功能所做的进一步研究。他们的调查结果为偏头痛的血小板假说提供了有力的额外支持。
