Ota Yoshihide, Sasaki Masashi
Department of Oral and Maxillofacial Surgery, Tokai University, School of Medicine, Japan.
Clin Calcium. 2016 Apr;26(4):612-21.
The mechanism and etiopathogenesis of medication-related osteonecrosis of the jaw (MRONJ) have never been unclear. Therefore, there is no consensus regarding the clinical management of patients with MRONJ. In Japan, Bisphosphonate-Related Osteonecrosis of the Jaw:Position Paper from the Allied Task Force Committee of Japanese Society for Bone and Mineral Research, Japan Osteoporosis Society, Japanese Society of Periodontology, Japanese Society for Oral and Maxillofacial, Radiology and Japanese Society of Oral and Maxillofacial Surgeons is frequently used as criterion. The purpose of this paper is discussing about MRONJ according to the Japanese position paper.
药物相关性颌骨坏死（MRONJ）的机制和病因一直不明确。因此，对于MRONJ患者的临床管理尚无共识。在日本，《日本骨与矿物质研究学会、日本骨质疏松症学会、日本牙周病学会、日本口腔颌面放射学会和日本口腔颌面外科医生学会联合特别工作组委员会关于双膦酸盐相关颌骨坏死的立场文件》经常被用作标准。本文旨在根据日本的立场文件讨论MRONJ。
