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[Consensus of Chinese experts on diagnosis and treatment of adult primary immune thrombocytopenia (version 2016)].

出版信息

Zhonghua Xue Ye Xue Za Zhi. 2016 Feb;37(2):89-93. doi: 10.3760/cma.j.issn.0253-2727.2016.02.001.

DOI:10.3760/cma.j.issn.0253-2727.2016.02.001
PMID:27014975
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7348205/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27f8/7348205/18f24325392b/cjh-37-02-089-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27f8/7348205/18f24325392b/cjh-37-02-089-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/27f8/7348205/18f24325392b/cjh-37-02-089-g001.jpg

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High-dose dexamethasone vs prednisone for treatment of adult immune thrombocytopenia: a prospective multicenter randomized trial.大剂量地塞米松与泼尼松治疗成人免疫性血小板减少症：一项前瞻性多中心随机试验。
Blood. 2016 Jan 21;127(3):296-302; quiz 370. doi: 10.1182/blood-2015-07-659656. Epub 2015 Oct 19.
2
Rituximab as second-line treatment for adult immune thrombocytopenia (the RITP trial): a multicentre, randomised, double-blind, placebo-controlled trial.利妥昔单抗二线治疗成人免疫性血小板减少症（RITP 试验）：一项多中心、随机、双盲、安慰剂对照试验。
Lancet. 2015 Apr 25;385(9978):1653-61. doi: 10.1016/S0140-6736(14)61495-1. Epub 2015 Feb 5.
3
Resveratrol inhibits AhR/Notch axis and reverses Th17/Treg imbalance in purpura by activating Foxp3.
白藜芦醇通过激活叉头框蛋白3（Foxp3）抑制芳烃受体（AhR）/Notch轴，并逆转紫癜中辅助性T细胞17（Th17）/调节性T细胞（Treg）失衡。
Toxicol Res (Camb). 2023 Apr 20;12(3):381-391. doi: 10.1093/toxres/tfad021. eCollection 2023 Jun.
4
A Nomogram Model for Individualized Prediction of the Risk of Respiratory Tract Infection within Six Months after Diagnosis in Patients with Primary Immune Thrombocytopenia.一种用于预测原发性免疫性血小板减少症患者诊断后 6 个月内呼吸道感染风险的列线图模型。
Comput Math Methods Med. 2022 Jul 28;2022:5002681. doi: 10.1155/2022/5002681. eCollection 2022.
5
Plasma Metabolomics Identifies the Dysregulated Metabolic Profile of Primary Immune Thrombocytopenia (ITP) Based on GC-MS.基于气相色谱-质谱联用技术的血浆代谢组学鉴定原发性免疫性血小板减少症（ITP）的代谢紊乱特征
Front Pharmacol. 2022 May 24;13:845275. doi: 10.3389/fphar.2022.845275. eCollection 2022.
6
A polygenic stacking classifier revealed the complicated platelet transcriptomic landscape of adult immune thrombocytopenia.一种多基因叠加分类器揭示了成人免疫性血小板减少症复杂的血小板转录组图谱。
Mol Ther Nucleic Acids. 2022 Apr 6;28:477-487. doi: 10.1016/j.omtn.2022.04.004. eCollection 2022 Jun 14.
7
Clinical and laboratory features of primary Sjögren's syndrome complicated with mild to severe thrombocytopenia.原发性干燥综合征合并轻至重度血小板减少症的临床及实验室特征
Ann Transl Med. 2022 Mar;10(6):300. doi: 10.21037/atm-22-162.
8
SDF-1 Facilitates Mesenchymal Stem Cells to Induce Regulatory B Cell Differentiation from Patients with Immune Thrombocytopenia.基质细胞衍生因子-1促进间充质干细胞诱导免疫性血小板减少症患者调节性B细胞分化。
Stem Cells Int. 2021 Nov 8;2021:3254488. doi: 10.1155/2021/3254488. eCollection 2021.
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Chronic Refractory Immune Thrombocytopenia Is Associated With Variants in Immune Genes.慢性难治性免疫性血小板减少症与免疫基因变异有关。
Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211059813. doi: 10.1177/10760296211059813.
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Regulation of Th1/Th2 and Th17/Treg by pDC/mDC imbalance in primary immune thrombocytopenia.原发免疫性血小板减少症中 pDC/mDC 失衡对 Th1/Th2 和 Th17/Treg 的调控作用。
Exp Biol Med (Maywood). 2021 Aug;246(15):1688-1697. doi: 10.1177/15353702211009787. Epub 2021 May 2.
A multicenter randomized open-label study of rituximab plus rhTPO vs rituximab in corticosteroid-resistant or relapsed ITP.
利妥昔单抗联合重组人血小板生成素对比利妥昔单抗治疗糖皮质激素抵抗或复发的免疫性血小板减少症的多中心随机开放标签研究
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Safety and efficacy of rituximab in adult immune thrombocytopenia: results from a prospective registry including 248 patients.利妥昔单抗治疗成人免疫性血小板减少症的安全性和有效性：一项前瞻性登记研究，纳入 248 例患者。
Blood. 2014 Nov 20;124(22):3228-36. doi: 10.1182/blood-2014-06-582346. Epub 2014 Oct 7.
5
Rituximab and three dexamethasone cycles provide responses similar to splenectomy in women and those with immune thrombocytopenia of less than two years duration.利妥昔单抗与三个地塞米松疗程对女性及免疫性血小板减少症病程少于两年者的疗效与脾切除术相似。
Haematologica. 2014 Jul;99(7):1264-71. doi: 10.3324/haematol.2013.103291. Epub 2014 Apr 18.
6
Splenectomy and the incidence of venous thromboembolism and sepsis in patients with immune thrombocytopenia.脾切除术与免疫性血小板减少症患者静脉血栓栓塞和脓毒症的发生率。
Blood. 2013 Jun 6;121(23):4782-90. doi: 10.1182/blood-2012-12-467068. Epub 2013 May 1.
7
Long-term treatment with romiplostim in patients with chronic immune thrombocytopenia: safety and efficacy.慢性免疫性血小板减少症患者使用罗米司亭的长期治疗：安全性和疗效。
Br J Haematol. 2013 May;161(3):411-23. doi: 10.1111/bjh.12260. Epub 2013 Feb 22.
8
Safety and efficacy of eltrombopag for treatment of chronic immune thrombocytopenia: results of the long-term, open-label EXTEND study.依曲泊帕治疗慢性免疫性血小板减少症的安全性和有效性：长期、开放性 EXTEND 研究结果。
Blood. 2013 Jan 17;121(3):537-45. doi: 10.1182/blood-2012-04-425512. Epub 2012 Nov 20.
9
A multicenter randomized controlled trial of recombinant human thrombopoietin treatment in patients with primary immune thrombocytopenia.一项重组人血小板生成素治疗原发免疫性血小板减少症患者的多中心随机对照试验。
Int J Hematol. 2012 Aug;96(2):222-8. doi: 10.1007/s12185-012-1124-8. Epub 2012 Jun 30.
10
Rituximab before splenectomy in adults with primary idiopathic thrombocytopenic purpura: a meta-analysis.利妥昔单抗治疗成人原发免疫性血小板减少症脾切除术前疗效的 Meta 分析。
Br J Haematol. 2012 Aug;158(3):386-98. doi: 10.1111/j.1365-2141.2012.09169.x. Epub 2012 May 22.