早期哺乳动物胚胎模式形成的分子先驱。
The Molecular Harbingers of Early Mammalian Embryo Patterning.
机构信息
Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
Gene Expression Laboratory, The Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.
出版信息
Cell. 2016 Mar 24;165(1):13-15. doi: 10.1016/j.cell.2016.03.005.
PMID:27015301
Abstract
Random or not, the mechanisms at play during the first cell-fate determination in mammalian embryos have been debated for years. Studies by Goolam et al. and White et al. shed new light on the molecular mechanisms underlying the intrinsic biases that lead to non-random lineage segregation in early mammalian development.
摘要
随机与否，哺乳动物胚胎中第一次细胞命运决定的作用机制多年来一直存在争议。Goolam 等人和 White 等人的研究为内在偏差导致早期哺乳动物发育中非随机谱系分离的分子机制提供了新的线索。
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