使用T2映射评估运动应激前后腰椎间盘的水分潴留情况。
Evaluation of Water Retention in Lumbar Intervertebral Disks Before and After Exercise Stress With T2 Mapping.
作者信息
Chokan Kou, Murakami Hideki, Endo Hirooki, Mimata Yoshikuni, Yamabe Daisuke, Tsukimura Itsuko, Oikawa Ryosuke, Doita Minoru
机构信息
Department of Orthopedic Surgery, School of Medicine, Iwate Medical University, Morioka, Japan.
出版信息
Spine (Phila Pa 1976). 2016 Apr;41(7):E430-6. doi: 10.1097/BRS.0000000000001283.
STUDY DESIGN
T2 mapping was used to quantify moisture content of the lumbar spinal disk nucleus pulposus (NP) and annulus fibrosus before and after exercise stress, and after rest, to evaluate the intervertebral disk function.
OBJECTIVE
To clarify water retention in intervertebral disks of the lumbar vertebrae by performing magnetic resonance imaging before and after exercise stress and quantitatively measuring changes in moisture content of intervertebral disks with T2 mapping.
SUMMARY OF BACKGROUND DATA
To date, a few case studies describe functional evaluation of articular cartilage with T2 mapping; however, T2 mapping to the functional evaluation of intervertebral disks has rarely been applied. Using T2 mapping might help detect changes in the moisture content of intervertebral disks, including articular cartilage, before and after exercise stress, thus enabling the evaluation of changes in water retention shock absorber function.
METHODS
Subjects, comprising 40 healthy individuals (males: 26, females: 14), underwent magnetic resonance imaging T2 mapping before and after exercise stress and after rest. Image J image analysis software was then used to set regions of interest in the obtained images of the anterior annulus fibrosus, posterior annulus fibrosus, and NP. T2 values were measured and compared according to upper vertebrae position and degeneration grade.
RESULTS
T2 values significantly decreased in the NP after exercise stress and significantly increased after rest. According to upper vertebrae position, in all of the upper vertebrae positions, T2 values for the NP significantly decreased after exercise stress and significantly increased after rest. According to the degeneration grade, in the NP of grade 1 and 2 cases, T2 values significantly decreased after exercise stress and significantly increased after rest.
CONCLUSION
T2 mapping could be used to not only diagnose the degree of degeneration but also evaluate intervertebral disk function.
LEVEL OF EVIDENCE
研究设计
采用T2映射技术量化运动应激前后及休息后腰椎间盘髓核（NP）和纤维环的水分含量，以评估椎间盘功能。
目的
通过运动应激前后进行磁共振成像，并利用T2映射技术定量测量椎间盘水分含量的变化，以阐明腰椎间盘的水分潴留情况。
背景数据总结
迄今为止，少数病例研究描述了利用T2映射技术对关节软骨进行功能评估；然而，T2映射技术在椎间盘功能评估中的应用却很少。使用T2映射技术可能有助于检测运动应激前后包括关节软骨在内的椎间盘水分含量的变化，从而能够评估水分潴留减震功能的变化。
方法
40名健康个体（男性26名，女性14名）作为研究对象，在运动应激前后及休息后接受磁共振成像T2映射检查。然后使用Image J图像分析软件在获得的前纤维环、后纤维环和NP图像中设置感兴趣区域。根据上位椎体位置和退变程度测量并比较T2值。
结果
运动应激后NP的T2值显著降低，休息后显著升高。根据上位椎体位置，在所有上位椎体位置，运动应激后NP的T2值均显著降低，休息后显著升高。根据退变程度，在1级和2级病例的NP中，运动应激后T2值显著降低，休息后显著升高。
结论
T2映射技术不仅可用于诊断退变程度，还可用于评估椎间盘功能。
证据水平
3级。
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