Liu Yao-sheng, He Qi-zhen, Liu Shu-bin, Jiang Wei-gang, Lei Ming-xing
Zhongguo Gu Shang. 2016 Jan;29(1):94-8.
Metastatic epidural compression of the spinal cord is a significant source of morbidity in patients with systemic cancer. With improvment of oncotheray, survival period in the patients is improving and metastatic cord compression is en- countered increasingly often. Surgical management performed for early circumferential decompression for the spinal cord com- pression with spine instability, and spine reconstruction performed. Patients with radiosensitive tumours without spine instabili- ty, radiotherapy is an effective therapy. Spinal stereotactic radiosurgery and minimally invasive techniques, such as vertebro- plasty and kyphoplasty, percutaneous pedicle screw fixation, radiofrequency ablation are promising options for treatment of cer- tain selected patients with spinal metastases.
脊髓转移性硬膜外压迫是全身癌症患者发病的重要原因。随着肿瘤治疗的进步,患者的生存期在延长,脊髓转移压迫也越来越常见。对于伴有脊柱不稳定的脊髓压迫,早期进行全周减压手术并进行脊柱重建。对于无脊柱不稳定的放射敏感性肿瘤患者,放疗是一种有效的治疗方法。脊柱立体定向放射外科和微创技术,如椎体成形术、后凸成形术、经皮椎弓根螺钉固定、射频消融,是某些特定脊髓转移患者有前景的治疗选择。