Dylag Mariusz
Med Dosw Mikrobiol. 2015;67(3-4):221-31.
A significant participation in the growing prevalence of fungal infections have basidiomycete yeasts of the genus of Cryptococcus. Among about seventy actually known species belonging to Cryptococcus genus there are only two: Cryptococcus neoformans and Cryptococcus gattii, which as anamorphs in parasitic stage of its life fully evolved the mechanisms predisposing them to be a human and animal pathogens. Specific attributes important in the pathogenesis of cryptococcosis called virulence factors allow them to colonize the mammalian tissues. Undoubtedly, the most important role in the pathogenesis play: the presence of polysaccharide capsule, synthesis of melanin, and the ability to grow in the range of temperatures 35-40°C.
隐球菌属的担子菌酵母在真菌感染日益流行中起着重要作用。在大约70种实际已知的隐球菌属物种中,只有两种:新型隐球菌和格特隐球菌,它们在其生命周期的寄生阶段作为无性型充分进化出了使其成为人类和动物病原体的机制。在隐球菌病发病机制中重要的特定属性即毒力因子,使它们能够在哺乳动物组织中定殖。在发病机制中无疑起着最重要作用的是:多糖荚膜的存在、黑色素的合成以及在35-40°C温度范围内生长的能力。