Lin Taichen, Aoki Akira, Saito Norihito, Yumoto Masaki, Nakajima Sadahiro, Nagasaka Keigo, Ichinose Shizuko, Mizutani Koji, Wada Satoshi, Izumi Yuichi
Department of Periodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University (TMDU), Tokyo, Japan.
Photonics Control Technology Team, Advanced Photonics Technology Development Group, RIKEN Center for Advanced Photonics, Riken, Wako, Saitama, Japan.
Lasers Surg Med. 2016 Dec;48(10):965-977. doi: 10.1002/lsm.22508. Epub 2016 Mar 29.
Mid-infrared erbium: yttrium-aluminum-garnet (Er:YAG) and erbium, chromium: yttrium-scandium-gallium-garnet (Er,Cr:YSGG) lasers (2.94- and 2.78-μm, respectively) are utilized for effective dental hard tissue treatment because of their high absorption in water, hydroxide ion, or both. Recently, a mid-infrared tunable, nanosecond pulsed, all-solid-state chromium-doped: cadmium-selenide (Cr:CdSe) laser system was developed, which enables laser oscillation in the broad spectral range around 2.9 μm. The purpose of this study was to evaluate the ablation of dental hard tissue by the nanosecond pulsed Cr:CdSe laser at a wavelength range of 2.76-3.00 μm.
STUDY DESIGN/MATERIALS AND METHODS: Enamel, dentin, and cementum tissue were irradiated at a spot or line at a fluence of 0-11.20 J/cm /pulse (energy output: 0-2.00 mJ/pulse) with a repetition rate of 10 Hz and beam diameter of ∼150 μm on the target (pulse width ∼250 ns). After irradiation, morphological changes, ablation threshold, depth, and efficiency, and thickness of the structurally and thermally affected layer of irradiated surfaces were analyzed using stereomicroscopy, scanning electron microscopy (SEM), and light microscopy of non-decalcified histological sections.
The nanosecond pulsed irradiation without water spray effectively ablated dental hard tissue with no visible thermal damage such as carbonization. The SEM analysis revealed characteristic micro-irregularities without major melting and cracks in the lased tissue. The ablation threshold of dentin was the lowest at 2.76 μm and the highest at 3.00 μm. The histological analysis revealed minimal thermal and structural changes ∼20 μm wide on the irradiated dentin surfaces with no significant differences between wavelengths. The efficiency of dentin ablation gradually increased from 3.00 to 2.76 μm, at which point the highest ablation efficiency was observed.
The nanosecond pulsed Cr:CdSe laser demonstrated an effective ablation ability of hard dental tissues, which was remarkably wavelength-dependent on dentin at the spectral range of 2.76-3.00 μm. These results demonstrate the potential feasibility of the use of pulsed Cr:CdSe laser as a novel laser system for dental treatment. Lasers Surg. Med. 48:965-977, 2016. © 2016 Wiley Periodicals, Inc.
中红外铒:钇铝石榴石(Er:YAG)和铒铬:钇钪镓石榴石(Er,Cr:YSGG)激光(分别为2.94微米和2.78微米)由于在水、氢氧根离子或两者中具有高吸收性,被用于有效的牙齿硬组织治疗。最近,开发了一种中红外可调谐、纳秒脉冲、全固态掺铬:硒化镉(Cr:CdSe)激光系统,该系统能够在2.9微米左右的宽光谱范围内实现激光振荡。本研究的目的是评估纳秒脉冲Cr:CdSe激光在2.76 - 3.00微米波长范围内对牙齿硬组织的消融情况。
研究设计/材料与方法:对牙釉质、牙本质和牙骨质组织进行光斑或线性照射,能量密度为0 - 11.20 J/cm²/脉冲(能量输出:0 - 2.00 mJ/脉冲),重复频率为10 Hz,靶上光束直径约为150微米(脉冲宽度约250纳秒)。照射后,使用体视显微镜、扫描电子显微镜(SEM)和未脱钙组织学切片的光学显微镜分析照射表面的形态变化、消融阈值、深度、效率以及结构和热影响层的厚度。
无水喷雾的纳秒脉冲照射有效地消融了牙齿硬组织,没有碳化等可见的热损伤。SEM分析显示激光照射组织具有特征性的微观不规则性,没有明显的熔化和裂纹。牙本质的消融阈值在2.76微米时最低,在3.00微米时最高。组织学分析显示照射的牙本质表面约20微米宽的热和结构变化最小,不同波长之间无显著差异。牙本质消融效率从3.00微米到2.76微米逐渐增加,在2.76微米时观察到最高消融效率。
纳秒脉冲Cr:CdSe激光显示出对牙齿硬组织有效的消融能力,在2.76 - 3.00微米光谱范围内对牙本质的消融能力显著依赖于波长。这些结果证明了使用脉冲Cr:CdSe激光作为新型牙科治疗激光系统的潜在可行性。《激光外科与医学》48:965 - 977,2016年。© 2016威利期刊公司