Ghasemi Younes, Rasoul-Amini Sara, Fotooh-Abadi Elham
Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Shiraz University of Medical Sciences, P.O. Box 71345-1583, Shiraz, Iran Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, P.O. Box 71345-158, Shiraz, Iran Department of Pharmaceutical Biotechnology, Faculty of Pharmacy, Shiraz University of Medical Sciences, P.O. Box 71345-1583, Shiraz, Iran Pharmaceutical Sciences Research Center, Shiraz University of Medical Sciences, P.O. Box 71345-158, Shiraz, Iran Department of Medicinal Chemistry, Faculty of Pharmacy, Shiraz University of Medical Sciences, P.O. Box 71345-1583, Shiraz, IranDepartment of Pharmaceutical Biotechnology, Faculty of Pharmacy, Shiraz University of Medical Sciences, P.O. Box 71345-1583, Shiraz, Iran.
J Phycol. 2011 Oct;47(5):969-80. doi: 10.1111/j.1529-8817.2011.01051.x. Epub 2011 Sep 13.
Rapid growth in the biotechnological industry and production has put tremendous pressure on the biological methods that may be used according to the guidelines of green chemistry. However, despite continuing dramatic increases in published research on organic biotransformation by microorganisms, more research exists with microalgae. Our efforts in transforming chemicals such as organic compounds for the production of functionalized products help to lessen the environmental effects of organic synthesis. These biotransformations convert organic contaminants to obtain carbon or energy for growth or as cosubstrates. This review aims to focus on the potential of microalgae in transformation, conversion, remediation, accumulation, degradation, and synthesis of various organic compounds. However, these technologies have the ability to provide the most efficient and environmentally safe approach for inexpensive biotransforming of a variety of organic contaminants, which are most industrial residues. In addition, the recent advances in microalgal bioactivity were discussed.
生物技术产业和生产的快速发展给可根据绿色化学指南使用的生物方法带来了巨大压力。然而,尽管关于微生物有机生物转化的已发表研究持续急剧增加,但针对微藻的研究更多。我们在转化有机化合物等化学品以生产功能化产品方面所做的努力有助于减轻有机合成对环境的影响。这些生物转化将有机污染物转化以获取生长所需的碳或能量或作为共底物。本综述旨在聚焦微藻在各种有机化合物的转化、转化、修复、积累、降解和合成方面的潜力。然而,这些技术有能力为各种有机污染物(其中大多数是工业残留物)的廉价生物转化提供最有效且环境安全的方法。此外,还讨论了微藻生物活性的最新进展。