钙结合蛋白、小白蛋白和钙结合蛋白在鸽子中脑听觉中枢（MLd）的分布。
Distribution of calcium-binding proteins, parvalbumin and calbindin, in the midbrain auditory center (MLd) of a pigeon.
作者信息
Belekhova M G, Kenigfest N B, Chudinova T V, Vesselkin N P
机构信息
Sechenov Institute of Evolutionary Physiology and Biochemistry, Russian Academy of Sciences, St. Petersburg, Russia.
出版信息
Dokl Biol Sci. 2016;466:1-4. doi: 10.1134/S001249661601004X. Epub 2016 Mar 30.
Immunohistochemical distribution of calcium-binding proteins, parvalbumin (PV) and calbindin (CB), has been studied in the mesencephalic auditory center (MLd) of pigeon (Columba livia). In the central region of the MLd (core, ICC), an overlap in distribution of the PVand CB-immunopositive (ip) neurons and neuropil has been observed, with different patterns in the central and peripheral parts. In the peripheral region of the MLd (belt, ICS, and ICX), both neurons and neuropil contained only CB. A selective CB chemospecificity of the belt, ICS, and ICX is an evolutionary conserved feature characteristic of all avian species. Interspecies differences in the distribution of PV and CB immunoreactivity in the ICC are a result of adaptive functional specialization, which provides specific processing of different aspects of the auditory information.
已对家鸽（Columba livia）中脑听觉中枢（MLd）中钙结合蛋白小白蛋白（PV）和钙结合蛋白（CB）的免疫组织化学分布进行了研究。在MLd的中央区域（核心，ICC），观察到PV和CB免疫阳性（ip）神经元及神经纤维网的分布存在重叠，中央和周边部分呈现不同模式。在MLd的周边区域（带状区、ICS和ICX），神经元和神经纤维网仅含有CB。带状区、ICS和ICX的选择性CB化学特异性是所有鸟类物种共有的进化保守特征。ICC中PV和CB免疫反应性分布的种间差异是适应性功能特化的结果，这为听觉信息不同方面的特定处理提供了条件。
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