Zhang Meng, Puska Mervi A, Botelho Michael G, Säilynoja Eija S, Matinlinna Jukka P
Dental Materials Science, Faculty of Dentistry, The University of Hong Kong.
J Oral Sci. 2016;58(1):15-22. doi: 10.2334/josnusd.58.15.
The degree of conversion (DC) and monomer leaching of three experimental urethane dimethacrylate (UEDMA)-hydroxypropyl methacrylate (HPMA)-based resin systems were studied. Three experimental resins (E1: 70.6 wt% UEDMA + 27.4 wt% HPMA, E2: 80.6 wt% UEDMA + 17.4 wt% HPMA, E3: 90.6 wt% UEDMA + 7.4 wt% HPMA) and one control resin [C: 70.6 wt% bis-phenol A glycidyl methacrylate (bis-GMA) + 27.4 wt% methyl methacrylate (MMA)] were prepared. For the DC test, cylindrical specimens [1.5 mm (h) × 6 mm (d)] were scanned with an ATR-FTIR instrument before and after light-curing (n = 5). For the monomer leaching test, block-shaped specimens [5.67 mm (l) × 2.00 mm (w) × 2.00 mm (h)] were light-cured (n = 6), stored in a 75% ethanol:water solution for 3 days, and then analyzed with HPLC. The UEDMA-HPMA-based experimental groups showed higher DC (62-78%) than the bis-GMA-MMA-based control group (58-66%), and the DC decreased as the UEDMA content increased (P < 0.05). Amongst the four groups, E3 exhibited the lowest leaching of both mono methacrylate (0.1% HPMA) and dimethacrylate (<0.043% UEDMA) monomers after 30 or 40 s of curing. The UEDMA-HPMA-based resins, therefore, exhibited higher DC and less monomer leaching compared to the bis-GMA-MMA-based resin. (J Oral Sci 58, 15-22, 2016).
研究了三种基于聚氨酯二甲基丙烯酸酯（UEDMA）-甲基丙烯酸羟丙酯（HPMA）的实验性树脂体系的转化率（DC）和单体浸出情况。制备了三种实验性树脂（E1：70.6 wt% UEDMA + 27.4 wt% HPMA，E2：80.6 wt% UEDMA + 17.4 wt% HPMA，E3：90.6 wt% UEDMA + 7.4 wt% HPMA）和一种对照树脂[C：70.6 wt% 双酚A甲基丙烯酸缩水甘油酯（bis-GMA） + 27.4 wt% 甲基丙烯酸甲酯（MMA）]。对于DC测试，在光固化前后用衰减全反射傅里叶变换红外光谱（ATR-FTIR）仪器扫描圆柱形试样[1.5毫米（高）×6毫米（直径）]（n = 5）。对于单体浸出测试，将块状试样[5.67毫米（长）×2.00毫米（宽）×2.00毫米（高）]进行光固化（n = 6），在75%乙醇：水溶液中储存3天，然后用高效液相色谱（HPLC）进行分析。基于UEDMA-HPMA的实验组显示出比基于双酚A甲基丙烯酸缩水甘油酯-甲基丙烯酸甲酯的对照组更高的DC（62-78%），且随着UEDMA含量的增加DC降低（P < 0.05）。在这四组中，E3在固化30或40秒后，单甲基丙烯酸酯（0.1% HPMA）和二甲基丙烯酸酯（<0.043% UEDMA）单体的浸出量最低。因此，与基于双酚A甲基丙烯酸缩水甘油酯-甲基丙烯酸甲酯的树脂相比，基于UEDMA-HPMA的树脂表现出更高的DC和更少的单体浸出。（《口腔科学杂志》58，15-22，2016）
