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AMERICAN ASSOCIATION OF CLINICAL ENDOCRINOLOGISTS AND AMERICAN COLLEGE OF ENDOCRINOLOGY 2016 OUTPATIENT GLUCOSE MONITORING CONSENSUS STATEMENT.美国临床内分泌医师协会和美国内分泌学会2016年门诊血糖监测共识声明
Endocr Pract. 2016 Feb;22(2):231-61. doi: 10.4158/EP151124.CS. Epub 2016 Jan 27.
2
Risk Factors Associated With Severe Hypoglycemia in Older Adults With Type 1 Diabetes.与 1 型糖尿病老年患者严重低血糖相关的危险因素。
Diabetes Care. 2016 Apr;39(4):603-10. doi: 10.2337/dc15-1426. Epub 2015 Dec 17.
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Understanding the sources of diabetes distress in adults with type 1 diabetes.了解1型糖尿病成年患者的糖尿病困扰来源。
J Diabetes Complications. 2015 May-Jun;29(4):572-7. doi: 10.1016/j.jdiacomp.2015.01.012. Epub 2015 Feb 7.
4
Personal real-time continuous glucose monitoring in patients 65 years and older.65 岁及以上患者的个人实时连续血糖监测。
Endocr Pract. 2014 Dec;20(12):1297-302. doi: 10.4158/EP14017.OR.
5
National trends in US hospital admissions for hyperglycemia and hypoglycemia among Medicare beneficiaries, 1999 to 2011.1999年至2011年美国医疗保险受益人因高血糖和低血糖住院的全国趋势。
JAMA Intern Med. 2014 Jul;174(7):1116-24. doi: 10.1001/jamainternmed.2014.1824.
6
National estimates of insulin-related hypoglycemia and errors leading to emergency department visits and hospitalizations.全国胰岛素相关低血糖及导致急诊就诊和住院的差错的估计数。
JAMA Intern Med. 2014 May;174(5):678-86. doi: 10.1001/jamainternmed.2014.136.
7
Severe hypoglycemia and diabetic ketoacidosis in adults with type 1 diabetes: results from the T1D Exchange clinic registry.成人 1 型糖尿病患者的严重低血糖和糖尿病酮症酸中毒:来自 T1D Exchange 诊所注册的结果。
J Clin Endocrinol Metab. 2013 Aug;98(8):3411-9. doi: 10.1210/jc.2013-1589. Epub 2013 Jun 12.
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What are the quality of life-related benefits and losses associated with real-time continuous glucose monitoring? A survey of current users.实时连续血糖监测相关的生活质量获益和损失有哪些?一项对当前使用者的调查。
Diabetes Technol Ther. 2013 Apr;15(4):295-301. doi: 10.1089/dia.2012.0298. Epub 2013 Feb 21.
9
Psychometric and screening properties of the WHO-5 well-being index in adult outpatients with Type 1 or Type 2 diabetes mellitus.1 型或 2 型糖尿病成年门诊患者 WHO-5 幸福指数的心理计量学和筛查特性。
Diabet Med. 2013 Feb;30(2):e63-9. doi: 10.1111/dme.12040.
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实时连续血糖监测对65岁及以上患者的影响。

The Impact of Real-Time Continuous Glucose Monitoring in Patients 65 Years and Older.

作者信息

Polonsky William H, Peters Anne L, Hessler Danielle

机构信息

University of California, San Diego, CA, USA Behavioral Diabetes Institute, San Diego, CA, USA

University of Southern California, Los Angeles, CA, USA.

出版信息

J Diabetes Sci Technol. 2016 Jun 28;10(4):892-7. doi: 10.1177/1932296816643542. Print 2016 Jul.

DOI:10.1177/1932296816643542
PMID:27022095
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4928238/
Abstract

BACKGROUND

Older adults with type 1 diabetes (T1D) or insulin-using type 2 diabetes (iT2D) are at high risk for severe hypoglycemic episodes. Real-time continuous glucose monitoring (RT-CGM) in this population may reduce this risk, but when patients switch to Medicare at age 65, RT-CGM is no longer a covered benefit. We developed a survey to examine health and quality of life (QOL) benefits of RT-CGM in seniors (age ≥ 65).

METHODS

Two groups of seniors with T1D or iT2D-current RT-CGM users (n = 210) and RT-CGM "hopefuls" (patients who wanted but could not obtain RT-CGM due to lack of insurance coverage; n = 75)-completed an online survey. The survey examined history of hypoglycemic experiences as well as current quality of life (QOL), including generic and diabetes-specific measures.

RESULTS

Current users reported fewer moderate (P < .01) and fewer severe hypoglycemic episodes (P < .01) over the past 6 months than "hopefuls" and greater reductions over time in hypoglycemic events requiring the assistance of another, ER visits, and paramedic visits to the home (in all cases, P < .01). Regarding QOL, current users reported significantly better well-being (P < .001), less hypoglycemic fear (P < .05), and less diabetes distress (P < .05) than "hopefuls."

CONCLUSIONS

These data suggest that RT-CGM use in seniors is associated with reductions in episodes of severe hypoglycemia and improved QOL, suggesting that restrictive access to RT-CGM in the Medicare age population may have deleterious health, economic, and QOL consequences.

摘要

背景

1型糖尿病(T1D)或使用胰岛素的2型糖尿病(iT2D)老年患者发生严重低血糖事件的风险较高。该人群使用实时连续血糖监测(RT-CGM)可能会降低这种风险,但当患者65岁转为医疗保险时,RT-CGM不再是一项涵盖的福利。我们开展了一项调查,以研究RT-CGM对老年人(年龄≥65岁)健康和生活质量(QOL)的益处。

方法

两组患有T1D或iT2D的老年人——当前的RT-CGM使用者(n = 210)和RT-CGM“渴望者”(因缺乏保险覆盖而想要但无法获得RT-CGM的患者;n = 75)——完成了一项在线调查。该调查考察了低血糖经历史以及当前的生活质量(QOL),包括一般和糖尿病特异性指标。

结果

与“渴望者”相比,当前使用者在过去6个月中报告的中度低血糖事件(P < .01)和严重低血糖事件较少(P < .01),并且随着时间推移,在需要他人协助的低血糖事件、急诊就诊以及护理人员上门就诊方面的减少幅度更大(在所有情况下,P < .01)。关于生活质量,当前使用者报告的幸福感明显更好(P < .001),低血糖恐惧更少(P < .05),糖尿病困扰更少(P < .05)。

结论

这些数据表明,老年人使用RT-CGM与严重低血糖事件发作减少和生活质量改善相关,这表明医疗保险年龄人群对RT-CGM的限制使用可能会对健康、经济和生活质量产生有害影响。