Dolgikh O V, Krivtsov A M, Starkova K G, Boubnova O A, Dianova D G, Vdovina N A, Uhabov V M
Med Tr Prom Ekol. 2015(12):21-5.
Comparative analysis covered immune genetic parameters in nonferrous metallurgy workers. The authors demonstrated differences in immune genetic profile between male and female workers, under exposure to combination of occupational hazards: noise and dust. Analysis of gene polymorphism revealed predominant disorders in the female workers, concerning criterion of prevalence for minor allele of genes in 1 and 2 phases of detoxication, neuro-endocrine regulation, lipid and energy metabolism, genes of immune regulation and apoptosis.
比较分析涵盖了有色冶金工人的免疫遗传参数。作者证明了在接触职业危害因素（噪音和粉尘）组合的情况下，男性和女性工人的免疫遗传特征存在差异。基因多态性分析显示，在解毒、神经内分泌调节、脂质和能量代谢、免疫调节和细胞凋亡的1期和2期基因的次要等位基因流行率标准方面，女性工人存在主要紊乱。
