Urology Department, Oslo University Hospital, 0424 Oslo, Norway.
Urology Department, Technical University of Munich, Munich 81675, Germany.
Antibiotics (Basel). 2014 Aug 14;3(3):375-7. doi: 10.3390/antibiotics3030375.
Urinary tract infections (UTI) are among the most frequently acquired infections in the community, but also in hospitals and other health care institutions, causing a huge amount of antibiotic consumption. During the last decade we have seen significant changes in the field of urinary tract infections regarding causative pathogens and antibiotic treatment calling for an update of current trends. The worldwide increase of uropathogens resistant to former first line antibiotics, such as cotrimoxazole, fluoroquinolones and cephalosporins, has had detrimental consequences not only for treatment but also for prophylaxis of infectious complications after urological interventions. A paradigm shift concerning asymptomatic bacteriuria has had a great impact on the definition and management of UTIs today [1-4]. [...].
尿路感染(UTI)是社区中最常见的感染之一,但在医院和其他医疗机构中也很常见,导致大量抗生素的使用。在过去的十年中,我们看到尿路感染领域在病原体和抗生素治疗方面发生了重大变化,因此需要更新当前的趋势。全球范围内,以前的一线抗生素,如复方磺胺甲噁唑、氟喹诺酮类和头孢菌素类,对尿路病原体的耐药性显著增加,这不仅对治疗,而且对泌尿外科手术后感染并发症的预防都产生了不利影响。无症状菌尿症的观念转变对 UTI 的定义和管理产生了重大影响[1-4]。[... ]。