Lapage Koen G, Wouters Patrick F
Department of Anesthesia and Perioperative Medicine, Ghent University and Ghent University Hospital, Ghent, Belgium.
Curr Opin Anaesthesiol. 2016 Jun;29(3):397-402. doi: 10.1097/ACO.0000000000000343.
General recommendations for the perioperative management of patients with hypertensive disease have not evolved much over the past 20 years, yet new pathophysiological concepts have emerged and new monitoring techniques are available today. In this review, we will discuss their significance and potential role in the modern perioperative care of hypertensive patients.
For hypertensive patients, total cardiovascular risk rather than blood pressure (BP) alone should determine the preoperative strategy. Except for grade 3 hypertension, surgery should not be deferred on the basis of an elevated BP in the preoperative assessment.New data suggest that even brief hypotensive episodes during surgery may have significant impact on outcome. Isolated systolic hypertension is the predominant phenotype in elderly patients who may be particularly vulnerable to hypoperfusion in the perioperative setting.New monitoring techniques such as echocardiography and near-infrared spectroscopy may provide crucial information to optimize intraoperative control of BP based on an individual patient's pathophysiology.
Hypertension is highly prevalent in patients presenting for surgery yet its impact on surgical outcome is still debated. Guidelines on risk stratification and perioperative hemodynamic management of patients with hypertensive disease remain sparse and cannot rely much on solid new evidence. Target organ damage associated with hypertensive disease rather than high BP per se appears to determine perioperative risk. In the absence of new data, an individualized and pathophysiology-based approach to control BP may be the best option to guide these patients through the perioperative period.
在过去20年里,高血压疾病患者围手术期管理的一般建议变化不大,但新的病理生理概念已经出现,并且如今有了新的监测技术。在本综述中,我们将讨论它们在高血压患者现代围手术期护理中的意义和潜在作用。
对于高血压患者,应根据总的心血管风险而非仅血压来确定术前策略。除3级高血压外,不应因术前评估血压升高而推迟手术。新数据表明,即使手术期间短暂的低血压发作也可能对预后产生重大影响。单纯收缩期高血压是老年患者的主要表型,他们在围手术期可能特别容易发生低灌注。新的监测技术,如超声心动图和近红外光谱,可能提供关键信息,以便根据个体患者的病理生理情况优化术中血压控制。
高血压在接受手术的患者中非常普遍,但其对手术结果的影响仍存在争议。关于高血压疾病患者风险分层和围手术期血流动力学管理的指南仍然很少,且很大程度上无法依赖确凿的新证据。与高血压疾病相关的靶器官损害而非高血压本身似乎决定了围手术期风险。在缺乏新数据的情况下,基于个体情况和病理生理的血压控制方法可能是指导这些患者度过围手术期的最佳选择。