Tóth Gábor, Bucher Franziska, Siebelmann Sebastian, Bachmann Björn, Hermann Manuel, Szentmáry Nóra, Nagy Zoltán Zsolt, Cursiefen Claus
*Department of Ophthalmology, Semmelweis University, Budapest, Hungary; †Department of Ophthalmology, University of Cologne, Cologne, Germany; and ‡Department of Ophthalmology, Saarland University Medical Center, Homburg, Saar, Germany.
Cornea. 2016 Jun;35(6):884-7. doi: 10.1097/ICO.0000000000000830.
To present a new treatment modality for recurrent corneal melting in a patient with a Boston type I keratoprosthesis (B-KPro) including in situ corneal cross-linking (CXL) and lamellar keratoplasty (LKP) as combined treatment.
Case report.
Our report concerns a 27-year-old man whose case history involved a severe chemical burn of his left eye. After failed penetrating keratoplasty and limbal stem cell transplantation, the patient underwent B-KPro implantation. Starting 1 month after surgery, recurrent corneal melting around the B-KPro developed, which was eventually treated by combining LKP, amniotic membrane transplantation, and in situ CXL. Optical coherence tomography imaging and follow-up for 12 months showed stable corneal healing without new melting or erosion. The ultraviolet A treatment did not seem to damage the material of the B-KPro.
In situ CXL using riboflavin and ultraviolet A light combined with LKP and amniotic membrane transplantation can be an effective management option to treat recurrent corneal melting after B-KPro implantation.
