Sahakyan Mushegh A, Kazaryan Airazat M, Pomianowska Ewa, Abildgaard Andreas, Line Pål-Dag, Bjørnbeth Bjørn Atle, Edwin Bjørn, Røsok Bård Ingvald
The Intervention Centre, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway; Institute of Clinical Research, Medical Faculty, University of Oslo, 0318 Oslo, Norway; Department of Surgery No. 1, Yerevan State Medical University after M. Heratsi, 0025 Yerevan, Armenia.
The Intervention Centre, Oslo University Hospital, Rikshospitalet, 0027 Oslo, Norway; Department of Gastrointestinal Surgery, Akershus University Hospital, 1478 Lørenskog, Norway.
Case Rep Oncol Med. 2016;2016:8946471. doi: 10.1155/2016/8946471. Epub 2016 Mar 1.
Background. Recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT) indicates a poor prognosis. Surgery is considered the only curative option for selected patients with HCC recurrence following LT. Traditionally, the preference is given to the open approach. Methods. In this report, we present two cases of laparoscopic resections (LR) for recurrent HCC after LT, performed at Oslo University Hospital, Rikshospitalet. Results. Both procedures were executed without intraoperative and postoperative adverse events. Whereas one of the patients had a recurrence one year after LR, the other patient did not have any sign of disease during 3-year follow-up. Conclusions. We argue that, in selected cases, patients with HCC recurrence following LT may benefit from LR due to its limited tissue trauma and timely start of subsequent treatment if curative resection cannot be obtained. In patients with relatively favorable prognosis, LR facilitates postoperative recovery course and avoids unnecessary laparotomy.
背景。肝移植（LT）后肝细胞癌（HCC）复发提示预后不良。手术被认为是肝移植后HCC复发的部分选定患者的唯一治愈选择。传统上，更倾向于开放手术方式。方法。在本报告中，我们介绍了在奥斯陆大学医院Rikshospitalet进行的两例肝移植后复发性HCC的腹腔镜切除术（LR）病例。结果。两个手术均未发生术中及术后不良事件。其中一名患者在腹腔镜切除术后一年复发，而另一名患者在3年随访期间未出现任何疾病迹象。结论。我们认为，在某些选定的病例中，肝移植后HCC复发的患者可能从腹腔镜切除术中获益，因为其组织创伤有限，并且如果无法进行根治性切除，可及时开始后续治疗。对于预后相对良好的患者，腹腔镜切除术有助于术后恢复过程并避免不必要的剖腹手术。
