Pavithran K
Dept. of Dermatology and Venereology, Medical College Hospital, Kottayam.
Indian J Lepr. 1989 Jan;61(1):44-8.
A middle-aged male with lepromatous leprosy developed bouts of skin lesions of depigmented macules and patches of vitiligo, just following attacks of type II lepra reaction each time. In view of the present concept of autoimmunity playing a role in the pathogenesis of vitiligo as well as lepra reaction, their association in our patient appears to be more than fortuious. The depigmented macules persisted even after regression of skin lesions of leprosy following chemotherapy. The vitiligo macules responded partially to topical and systemic psoralen therapy.
一名中年男性麻风瘤型麻风患者，每次在Ⅱ型麻风反应发作后，都会出现色素脱失斑和白癜风斑的皮肤病变发作。鉴于自身免疫在白癜风发病机制以及麻风反应中起作用的当前概念，它们在我们患者中的关联似乎并非偶然。即使在化疗后麻风皮肤病变消退后，色素脱失斑仍持续存在。白癜风斑对局部和全身补骨脂素治疗有部分反应。
