McComb P, Filmar S, Pabuccu R
Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, Canada.
J Reprod Med. 1989 Jan;34(1):55-8.
Loss of fertility due to prior segmental resection of the fallopian tube (for ectopic pregnancy or sterilization) can be treated with a free fimbrial graft, especially when the fimbrial segment is contralateral to the proximal tube that is needed for the anastomosis. To evaluate the structure and function of the fimbria after free grafting, the fimbria was cut from the tube and sewn without a blood supply to the peritoneum in 14 rabbits. After convalescence, scanning electron microscopy showed fewer secondary mucosal folds in the grafted fimbria than in the normal fimbria. The ciliated and secretory cells in the graft were identical to those of normal cells. The transport rate of surrogate ova across the grafted fimbrial mucosa was consistent with that across the normal fimbrial mucosa, demonstrating that near-normal structure and function are preserved after a free graft of the fimbria.
由于先前输卵管节段性切除（因异位妊娠或绝育）导致的生育能力丧失，可通过游离伞端移植进行治疗，尤其是当伞端节段与吻合所需的近端输卵管位于对侧时。为了评估游离移植后伞端的结构和功能，从输卵管上切下伞端并在无血供的情况下缝合到14只兔子的腹膜上。康复后，扫描电子显微镜显示移植的伞端中次级黏膜皱襞比正常伞端少。移植组织中的纤毛细胞和分泌细胞与正常细胞相同。替代卵子穿过移植伞端黏膜的转运速率与穿过正常伞端黏膜的转运速率一致，表明伞端游离移植后保留了接近正常的结构和功能。
