Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
Department of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing 100084, China.
Mater Sci Eng C Mater Biol Appl. 2016 Jun;63:657-62. doi: 10.1016/j.msec.2016.03.004. Epub 2016 Mar 4.
Wiping out counterfeit drugs is a great task for public health care around the world. The boost of these drugs makes treatment to become potentially harmful or even lethal. In this paper, biodegradable drug-laden QR code label for anti-counterfeiting of drugs is proposed that can provide the non-fluorescence recognition and high capacity. It is fabricated by the laser cutting to achieve the roughness over different surface which causes the difference in the gray levels on the translucent material the QR code pattern, and the micro mold process to obtain the drug-laden biodegradable label. We screened biomaterials presenting the relevant conditions and further requirements of the package. The drug-laden microlabel is on the surface of the troches or the bottom of the capsule and can be read by a simple smartphone QR code reader application. Labeling the pill directly and decoding the information successfully means more convenient and simple operation with non-fluorescence and high capacity in contrast to the traditional methods.
消灭假药是全球公共医疗保健的一项重大任务。这些假药的泛滥使得治疗变得潜在有害，甚至致命。在本文中，提出了一种用于药品防伪的可生物降解载药 QR 码标签，它可以提供非荧光识别和大容量。它是通过激光切割来实现不同表面的粗糙度，从而在半透明材料的 QR 码图案上产生灰度差异，并且通过微模具工艺获得载药的可生物降解标签。我们筛选了具有相关条件和包装进一步要求的生物材料。载药微标签位于锭剂的表面或胶囊的底部，可以通过简单的智能手机 QR 码读取器应用程序进行读取。与传统方法相比，直接对药丸进行标记并成功解码信息意味着操作更方便、更简单，且具有非荧光和大容量的优点。
