一名感染狂犬病的孕妇所产新生儿的存活情况。
Survival of a newborn from a pregnant woman with rabies infection.
作者信息
Qu Zhen-Yu, Li Guo-Wei, Chen Qiao-Ge, Jiang Peng, Liu Chang, Lam Alfred
机构信息
Department of Pathogenic Biology and Immunology, Luohe Medical College, Luohe, Henan 462002 PR China.
Department of Prevention and Control of Infectious diseases, Zhengzhou Center for Disease Control and Prevention, Zhengzhou, Henan 472000 China.
出版信息
J Venom Anim Toxins Incl Trop Dis. 2016 Apr 2;22:14. doi: 10.1186/s40409-016-0068-5. eCollection 2016.
BACKGROUND
Rabies is very common in People's Republic of China. Each year thousands of people die because of this disease, but rabies diagnosed in pregnancy is very rare.
CASE PRESENTATION
In this study, we report the case of a pregnant woman who was infected with the rabies virus after a dog bite. The symptoms of rabies appeared in labor and she died after pregnancy. Her baby and husband did not develop the disease.
CONCLUSION
The phenomenon that the newborn infant was healthy may be related to the protective role of placenta in resisting the invasion of the rabies virus or the absence of systemic viremia. The prompt administration of vaccines and anti-rabies immunoglobulin to the infant may have also contributed to his survival.
背景
狂犬病在中国非常常见。每年都有成千上万人死于这种疾病，但孕期诊断出狂犬病的情况非常罕见。
病例报告
在本研究中，我们报告了一名孕妇在被狗咬伤后感染狂犬病病毒的病例。狂犬病症状在分娩时出现，她在产后死亡。她的婴儿和丈夫未发病。
结论
新生儿健康这一现象可能与胎盘在抵抗狂犬病病毒入侵中的保护作用或缺乏全身性病毒血症有关。及时给婴儿接种疫苗和注射抗狂犬病免疫球蛋白也可能对其存活起到了作用。
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