Salmela Pasi, Metso Saara, Moilanen Leena, Niskanen Leo, Nuutila Pirjo, Schalin-Jäntti Camilla
Duodecim. 2016;132(1):33-42.
The diagnosis of hypothyroidism is based on the findings of an increased serum TSH (above the reference range) and decreased serum free T4 (below the reference range) concentration. Treatment of subclinical hypothyroidism is indicated if serum THS is above 10 mU/l. For less severe forms of subclinical hypothyroidism, the treatment should be individually tailored. The treatment of choice is synthetic human levothyroxine. The goals for treatment are amelioration of symptoms and normalization of TSH and free T4 concentrations.
甲状腺功能减退症的诊断基于血清促甲状腺激素(TSH)升高(高于参考范围)和血清游离甲状腺素(T4)浓度降低(低于参考范围)的检查结果。如果血清TSH高于10 mU/l,则需对亚临床甲状腺功能减退症进行治疗。对于不太严重的亚临床甲状腺功能减退症形式,治疗应个体化定制。治疗的首选药物是合成人左甲状腺素。治疗目标是缓解症状以及使TSH和游离T4浓度恢复正常。