Solovieva E Yu, Farrahova K I, Karneev A N, Chipova D T
GBOU VPO.
Rossijskij natsional'nyj issledovatel'skij meditsinskij universitet im. N.I. Pirogova', Moskva.
Zh Nevrol Psikhiatr Im S S Korsakova. 2016;116(1):104-112. doi: 10.17116/jnevro201611611104-112.
The disturbances of cerebral circulation results in the violation of phospholipid metabolism. Activation of lipid peroxidation and protein kinase C and release of intracellular calcium leads to disruption of the homeostasis of phosphatidylcholine. The use of cytidine-5-diphosphocholine, which is used as an intermediate compound in the biosynthesis of phospholipids of the cell membrane, helps to stabilize cell membranes, and reduce the formation of free radicals.
脑循环紊乱导致磷脂代谢异常。脂质过氧化、蛋白激酶C的激活以及细胞内钙的释放会导致磷脂酰胆碱稳态的破坏。胞苷-5-二磷酸胆碱作为细胞膜磷脂生物合成中的中间化合物，有助于稳定细胞膜并减少自由基的形成。
