De Carli Bethânia Molin Giaretta, Magro Alessandra Kuhn Dall, Souza-Silva Bianca Núbia, Matos Felipe de Souza, De Carli João Paulo, Paranhos Luiz Renato, Magro Eduardo Dall
School of Dentistry, University of Passo Fundo, Rio Grande do Sul, Brazil.
Department of Oral and Maxillofacial Surgery, Hospital São Vicente de Paulo de Passo Fundo, Rio Grande do Sul, Brazil.
J Photochem Photobiol B. 2016 Jun;159:120-3. doi: 10.1016/j.jphotobiol.2016.03.038. Epub 2016 Mar 29.
This study conducted a randomized clinical trial in 15 patients, who sought care at the Dental Clinic of the University of Passo Fundo, in order to compare the use of low-level laser and botulinum toxin in the treatment of myofascial pain and whether they alter the mouth opening of patients with temporomandibular disorder. The patients were divided into two groups: the Laser group received low-level GaAlAs laser, 100mW of power at a wavelength of 830nm in continuous light emission; and the Toxin group received 30U of botulinum toxin type A (BTX-A) in the first session, and 15U after fifteen days. The assessments were performed by measuring pain with Visual Analogue Scale (VAS), and mouth opening with a digital caliper. Data were submitted to Student's t test at 5% significance level. Regarding pain symptoms, the results indicate that groups treated with laser and toxin registered 7U in VAS, at day 5 the scores were 4.75 and 4.86U, respectively. The laser worked faster (day 12) at 2.75U, and the group treated with BTX-A registered 2.86U at day 30. Both therapies investigated were effective in reducing pain, but the effect of low-level laser was faster than the use of BTX-A. Both treatments showed no statistically significant improvement in mouth opening.
本研究对15名在南大河州联邦大学牙科诊所就诊的患者进行了一项随机临床试验，以比较低强度激光和肉毒杆菌毒素在治疗肌筋膜疼痛中的应用，以及它们是否会改变颞下颌关节紊乱患者的张口度。患者被分为两组：激光组接受波长为830nm、功率为100mW的连续发光的低强度镓铝砷激光；毒素组在第一阶段接受30U的A型肉毒杆菌毒素（BTX-A），15天后接受15U。通过视觉模拟量表（VAS）测量疼痛，并使用数字卡尺测量张口度来进行评估。数据在5%的显著性水平下进行学生t检验。关于疼痛症状，结果表明，激光组和毒素组在第5天的VAS评分均为7U，分别为4.75U和4.86U。激光起效更快（第12天），评分为2.75U，而BTX-A治疗组在第30天的评分为2.86U。所研究的两种疗法在减轻疼痛方面均有效，但低强度激光的效果比BTX-A更快。两种治疗方法在张口度方面均未显示出统计学上的显著改善。
