P-glycoprotein transporter in drug development.
作者信息
Prachayasittikul Veda, Prachayasittikul Virapong
机构信息
Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand; Dental Hospital Mahidol University Faculty of Dentistry, Faculty of Dentistry, Mahidol University, Bangkok 10400, Thailand.
Department of Clinical Microbiology and Applied Technology, Faculty of Medical Technology, Mahidol University, Bangkok 10700, Thailand.
出版信息
EXCLI J. 2016 Feb 12;15:113-8. doi: 10.17179/excli2015-768. eCollection 2016.
Abstract
摘要
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Exploring the Chemical Space of P-Glycoprotein Interacting Compounds.探索P-糖蛋白相互作用化合物的化学空间
Mini Rev Med Chem. 2017;17(14):1332-1345. doi: 10.2174/1389557516666160121120344.
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Computer-Aided Drug Design of Bioactive Natural Products.生物活性天然产物的计算机辅助药物设计
Curr Top Med Chem. 2015;15(18):1780-800. doi: 10.2174/1568026615666150506151101.
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Docking applied to the prediction of the affinity of compounds to P-glycoprotein.对接技术在预测化合物与P-糖蛋白亲和力中的应用。
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Invest New Drugs. 2014 Aug;32(4):618-25. doi: 10.1007/s10637-014-0098-1. Epub 2014 Apr 22.
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Expression of HIF-1α and MDR1/P-glycoprotein in refractory mesial temporal lobe epilepsy patients and pharmacoresistant temporal lobe epilepsy rat model kindled by coriaria lactone.马桑内酯点燃的难治性内侧颞叶癫痫患者及药物抵抗性颞叶癫痫大鼠模型中HIF-1α和MDR1/P-糖蛋白的表达
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Mol Pharm. 2014 Mar 3;11(3):716-26. doi: 10.1021/mp400450m. Epub 2014 Feb 18.
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A genetic algorithm- back propagation artificial neural network model to quantify the affinity of flavonoids toward P-glycoprotein.一种用于量化黄酮类化合物与P-糖蛋白亲和力的遗传算法-反向传播人工神经网络模型。
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