Cohen D J, Briggs R, Head H D, Acher C W
Cardiothoracic Surgery Service, Brooke Army Medical Center, Ft. Sam Houston, Texas.
Angiology. 1989 May;40(5):498-508. doi: 10.1177/000331978904000513.
Six patients who developed phlegmasia cerulea dolens are described. All patients had associated hypercoagulable states: heparin-induced thrombocytopenia (2 patients), congenital deficiency of protein C (1 patient), and antithrombin III deficiency (3 patients). Their clinical course and management are discussed. Previous reports have failed to show a definite correlation between phlegmasia cerulea dolens and hypercoagulable states because of an unavailability of appropriate diagnostic techniques. Phlegmasia cerulea dolens is a life- and limb-threatening complication. An appreciation of underlying hypercoagulable states is essential to proper management, prophylaxis, and treatment of this disorder.
本文描述了6例发生股青肿的患者。所有患者均伴有高凝状态:肝素诱导的血小板减少症(2例)、蛋白C先天性缺乏(1例)和抗凝血酶III缺乏(3例)。讨论了他们的临床病程及治疗情况。由于缺乏合适的诊断技术,既往报告未能显示股青肿与高凝状态之间存在明确关联。股青肿是一种危及生命和肢体的并发症。了解潜在的高凝状态对于该疾病的正确管理、预防和治疗至关重要。