Heinzmann-Filho João Paulo, Vendrusculo Fernanda Maria, Woszezenki Cristhiele Taís, Piva Taila Cristina, Santos Andressa Nunes, Barcellos Andressa Bombardi, Vagliatti Bruna Brufatto, Corrêa Débora Gonzales, Mattiello Rita, Donadio Márcio Vinícius Fagundes
a Graduate Program in Pediatrics and Child Health , Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) , Porto Alegre , Rio Grande do Sul , Brazil.
b School of Nursing , Nutrition and Physiotherapy, Pontifícia Universidade Católica do Rio Grande do Sul (PUCRS) , Porto Alegre , Rio Grande do Sul , Brazil.
J Asthma. 2016 Nov;53(9):893-9. doi: 10.3109/02770903.2016.1165698. Epub 2016 Apr 8.
To compare inspiratory muscle function (strength and endurance) between asthmatics and healthy controls, and the influence of age, nutritional status and physical activity on them.
This is a cross-sectional study. Asthmatic and healthy subjects, aged 6 to 18 years old, recruited from two public schools in Southern Brazil were included in the study. Asthmatic subjects were selected using the criteria presented by the International Study on Asthma and Allergies in Children and control subjects based on the absence of respiratory symptoms. Anthropometric data was measured, body mass index calculated and subjects classified as normal weight, overweight or obese. Physical activity levels, maximum inspiratory pressure (MIP) and inspiratory muscle endurance (IME) were also evaluated.
A total of 314 participants were included, separated into control group (181) and asthmatics (133), with a total mean age of 11 years. When both groups were compared, there were no significant differences in both MIP and IME. However, when groups were analyzed subdivided in children and adolescents, IME was significantly reduced (p = 0.003) in asthmatic adolescents. Indeed, when groups were also stratified considering the nutritional status, IME showed a reduction in asthmatic adolescents with overweight (p = 0.042) and obesity (p = 0.041) when compared to healthy controls. No effects of physical activity levels between groups were found.
Results demonstrate a reduction in the IME in asthmatic adolescents with overweight and obesity, indicating an association between asthma, nutritional status and respiratory muscle function.
比较哮喘患者与健康对照者的吸气肌功能（力量和耐力），以及年龄、营养状况和身体活动对其的影响。
这是一项横断面研究。从巴西南部的两所公立学校招募了6至18岁的哮喘患者和健康受试者纳入研究。根据儿童哮喘和过敏国际研究提出的标准选择哮喘患者，根据无呼吸道症状选择对照受试者。测量人体测量数据，计算体重指数，并将受试者分为正常体重、超重或肥胖。还评估了身体活动水平、最大吸气压力（MIP）和吸气肌耐力（IME）。
共纳入314名参与者，分为对照组（181名）和哮喘组（133名），总平均年龄为11岁。两组比较时，MIP和IME均无显著差异。然而，当按儿童和青少年亚组分析时，哮喘青少年的IME显著降低（p = 0.003）。实际上，当按营养状况对组进行分层时，与健康对照相比，超重（p = 0.042）和肥胖（p = 0.041）的哮喘青少年的IME降低。未发现两组之间身体活动水平的影响。
结果表明，超重和肥胖的哮喘青少年的IME降低，表明哮喘、营养状况和呼吸肌功能之间存在关联。
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