Palmer S R, Biffin A, Gamsu H R
Public Health Laboratory Service Communicable Disease Surveillance Centre, Cardiff.
Arch Dis Child. 1989 Mar;64(3):388-94. doi: 10.1136/adc.64.3.388.
Neonatologists in 100 special care baby units in the United Kingdom and Ireland collaborated in a four year surveillance study of neonatal necrotising enterocolitis. The average overall annual reporting rate of necrotising enterocolitis for infants in England and Wales was 0.3/1000 live births, but ranged from 9.5/1000 live births in infants weighing less than 1000 g at birth to 0.2/1000 live births in infants weighing 2500 g or more. There were more deaths among girls, infants who weighed less than 1500 g at birth, those whose bleeding was abnormal or who had low peripheral platelet counts, infants with Gram negative bacteraemia, and very low birthweight infants who developed it during the first few days of life. In both boys and girls, and in all birthweight groups, operation was associated with increased mortality.
英国和爱尔兰100个特殊护理婴儿病房的新生儿科医生合作开展了一项为期四年的新生儿坏死性小肠结肠炎监测研究。英格兰和威尔士婴儿坏死性小肠结肠炎的年总体报告率平均为0.3/1000活产，但范围从出生体重低于1000克的婴儿的9.5/1000活产到出生体重2500克或以上的婴儿的0.2/1000活产。女孩、出生体重低于1500克的婴儿、出血异常或外周血小板计数低的婴儿、革兰氏阴性菌血症婴儿以及出生体重极低且在出生后几天内发病的婴儿中死亡人数更多。在男孩和女孩以及所有出生体重组中，手术都与死亡率增加相关。
