Tomoda Takeshi, Tsutsumi Koichiro, Kato Hironari, Mizukawa Sho, Yabe Syuntaro, Akimoto Yutaka, Seki Hiroyuki, Uchida Daisuke, Matsumoto Kazuyuki, Yamamoto Naoki, Horiguchi Shigeru, Okada Hiroyuki
Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry, and Pharmaceutical Sciences, 2-5-1 Shikata-cho, Kita-ku, Okayama City, Okayama, 700-8558, Japan.
Surg Endosc. 2016 Dec;30(12):5338-5344. doi: 10.1007/s00464-016-4886-x. Epub 2016 Apr 8.
To evaluate the outcomes of management for biliary stricture (BS) after living donor liver transplantation (LDLT) using short-type double-balloon enteroscopy.
This study retrospectively evaluated 20 patients who underwent endoscopic retrograde cholangiography using short-type double-balloon enteroscopy (sDB-ERC) upon suspicion of BS after LDLT with hepaticojejunal (HJ) reconstruction at Okayama University Hospital.
Scope insertion to the HJ site and sDB-ERC succeeded in 85 % (17/20) and 82.4 % (14/17) of patients, respectively. Of 14 patients who required treatment for BS, 11 were successfully treated using sDB-ERC, and 3 were successfully treated using sDB-ERC and rendezvous procedures. Adverse events occurred in 2.9 % of all sessions (2/68). After resolution of BS, 7 patients (50 %) experienced a recurrence. Of these, 6 (85.7 %) were treated with only balloon dilation, and 1 (14.3 %) was treated with both balloon dilation and stent deployment (P = 0.029).
sDB-ERC is a useful procedure for diagnosis and treatment for BS after LDLT with HJ reconstruction. Balloon dilation combined with stent deployment might be recommended for definite resolution of BS.
评估使用短型双气囊小肠镜对活体肝移植(LDLT)术后胆管狭窄(BS)的治疗效果。
本研究回顾性评估了20例在冈山大学医院接受肝空肠(HJ)重建的LDLT术后疑似BS的患者,这些患者接受了短型双气囊小肠镜检查(sDB - ERC)下的内镜逆行胆管造影。
分别有85%(17/20)的患者成功将内镜插入至HJ部位,82.4%(14/17)的患者成功完成sDB - ERC。在14例需要治疗BS的患者中,11例使用sDB - ERC成功治疗,3例使用sDB - ERC和会师操作成功治疗。所有操作中2.9%(2/68)发生不良事件。BS缓解后,7例患者(50%)复发。其中,6例(85.7%)仅接受球囊扩张治疗,1例(14.3%)接受球囊扩张和支架置入联合治疗(P = 0.029)。
sDB - ERC是对接受HJ重建的LDLT术后BS进行诊断和治疗的有效方法。对于明确解决BS,可能建议球囊扩张联合支架置入。