Mosca Ralph S, Phoon Colin K L
George E. Reed Professor of Cardiac Surgery Vice Chairman, Clinical Affairs, Chief, Division of Congenital Cardiac Surgery, NYU Langone Medical Center, New York, NY.
Division of Pediatric Cardiology, NYU Langone Medical Center, New York, NY.
Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2016;19(1):30-6. doi: 10.1053/j.pcsu.2015.12.006.
Anomalous aortic origin of the coronary artery (AAOCA) from the opposite sinus of Valsalva with an interarterial course has become a high-profile lesion as a result of its association with sudden cardiac death in otherwise young and healthy individuals. Despite our incomplete knowledge of its pathophysiology and natural history, surgical intervention is often recommended. Evidence now shows AAOCA to be relatively common, with lower than previously suspected rates of sudden cardiac death. Analysis of this information reveals that AAOCA is not always a surgical disease. Future multi-institutional studies will continue to define those subgroups best served by observation or surgery.
起源于对侧瓦尔萨尔瓦窦且走行于动脉之间的冠状动脉异常起源（AAOCA），因其与原本年轻健康个体的心脏性猝死相关，已成为备受瞩目的病变。尽管我们对其病理生理学和自然史了解不全面，但通常仍建议进行手术干预。目前有证据表明AAOCA相对常见，心脏性猝死发生率低于先前的怀疑。对这些信息的分析显示，AAOCA并不总是一种需要手术治疗的疾病。未来的多机构研究将继续明确那些最适合观察或手术治疗的亚组。
