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强化肺动脉自体移植Ross手术后的长期临床及影像学随访

Long-Term Clinical and Imaging Follow-Up After Reinforced Pulmonary Autograft Ross Procedure.

作者信息

Carrel Thierry, Kadner Alexander

机构信息

Clinic for Cardiovascular Surgery, University Hospital and University of Bern, Switzerland.

Clinic for Cardiovascular Surgery, University Hospital and University of Bern, Switzerland.

出版信息

Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu. 2016;19(1):59-62. doi: 10.1053/j.pcsu.2015.11.005.

Abstract

The Ross operation remains a controversially discussed procedure when performed in the full root technique because concern exists regarding late dilatation of the pulmonary autograft and regurgitation of the neo-aortic valve. In 2008, we published our short-term experience when using external reinforcement of the autograft, which was inserted into a prosthetic Dacron graft. This detail was thought to prevent neoaortic root dilatation. Since 2006, 22 adult patients have undergone a Ross procedure using this technique. Indications were aortic regurgitation (n = 2), aortic stenosis (n = 15), and combined aortic stenosis and insufficiency (n = 5). A bicuspid aortic valve was present in 10 patients. Prior balloon valvuloplasty had been performed in seven patients. No early or late deaths occurred in this small series. One patient required aortic valve replacement early postoperatively, but freedom from late reoperation is 100% in the 21 remaining patients. Echocardiography confirmed the absence of more than trivial aortic insufficiency in 15 patients after a mean of 70 months (range, 14 to 108 months). No autograft dilatation was observed during follow-up and all patients are in New York Heart Association Class I. Autograft reinforcement is a simple and reproducible technical adjunct that may be especially useful in situations known for late autograft dilatation, namely, bicuspid aortic valve, predominant aortic insufficiency, and ascending aortic enlargement. The mid- to long-term results are encouraging because no late aortic root enlargement has been observed and the autograft valve is well functioning in all cases.

摘要

当采用全根部技术进行Ross手术时,该手术仍存在争议,因为人们担心肺动脉自体移植物的晚期扩张和新主动脉瓣的反流。2008年,我们发表了使用自体移植物外部加固的短期经验,即把自体移植物植入人工涤纶补片。这一细节被认为可防止新主动脉根部扩张。自2006年以来,22例成年患者采用该技术接受了Ross手术。手术指征包括主动脉瓣反流(n = 2)、主动脉瓣狭窄(n = 15)以及主动脉瓣狭窄合并关闭不全(n = 5)。10例患者存在二叶式主动脉瓣。7例患者曾接受过球囊瓣膜成形术。在这个小样本系列中未发生早期或晚期死亡。1例患者术后早期需要进行主动脉瓣置换,但其余21例患者的晚期再次手术率为100%。平均70个月(范围14至108个月)后,超声心动图证实15例患者的主动脉瓣反流不超过轻度。随访期间未观察到自体移植物扩张,所有患者的心功能均为纽约心脏协会I级。自体移植物加固是一种简单且可重复的技术辅助手段,在已知会发生自体移植物晚期扩张的情况下可能特别有用,即二叶式主动脉瓣、以主动脉瓣反流为主以及升主动脉增宽。中长期结果令人鼓舞,因为未观察到晚期主动脉根部扩大,且所有病例中的自体移植物瓣膜功能良好。

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