Abedini Robabeh, Kamyab Hesari Kambiz, Daneshpazhooh Maryam, Ansari Mahshid Sadat, Tohidinik Hamid Reza, Ansari Mahsa
Department of Dermatology, Autoimmune Bullous Diseases Research Center, Tehran University of Medical Sciences, Tehran, Iran.
Department of Dermatopathology, Razi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Int J Dermatol. 2016 Oct;55(10):1106-14. doi: 10.1111/ijd.13304. Epub 2016 Apr 7.
There are limited data on the validity of dermatoscopy in primary cicatricial alopecias (PCAs) and its subtypes, including lichen planopilaris and discoid lupus erythematosus. Trichoscopic features of PCAs, their prevalence, and validity were evaluated in this study.
One hundred patients with PCA underwent dermatoscopy. Biopsy specimens were obtained after the site was marked with a dermatoscope. The control group comprised 100 patients with non-cicatricial alopecia and 100 normal individuals. Finally, the prevalence, sensitivity, and specificity of trichoscopic features were evaluated using SPSS and Stata software.
The absence of follicular opening, perifollicular scale, and presence of one scarring pattern or white patch were sensitive and specific patterns in the trichoscopy of PCAs. The presence of tortuous branching vessels and follicular keratotic plugging was 100% specific for a diagnosis of discoid lupus erythematosus.
Some trichoscopic features can help a dermatologist to differentiate between non-cicatricial alopecia and PCA. Moreover, a group of dermatoscopic features can be helpful in the diagnosis of PCA subtypes.
关于皮肤镜检查在原发性瘢痕性脱发（PCA）及其亚型（包括扁平苔藓样毛发扁平苔藓和盘状红斑狼疮）中的有效性的数据有限。本研究评估了PCA的毛发镜特征、其患病率及有效性。
100例PCA患者接受了皮肤镜检查。在皮肤镜标记部位后获取活检标本。对照组包括100例非瘢痕性脱发患者和100名正常个体。最后，使用SPSS和Stata软件评估毛发镜特征的患病率、敏感性和特异性。
在PCA的毛发镜检查中，毛囊开口缺失、毛囊周围鳞屑以及存在一种瘢痕模式或白色斑块是敏感且特异的模式。迂曲分支血管和毛囊角质栓的存在对盘状红斑狼疮的诊断具有100%的特异性。
一些毛发镜特征可帮助皮肤科医生区分非瘢痕性脱发和PCA。此外，一组皮肤镜特征有助于PCA亚型的诊断。
