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欣奇 I 型和 II 型憩室脓肿:保守治疗的长期结果

Hinchey I and II diverticular abscesses: long-term outcome of conservative treatment.

作者信息

Buchwald Pamela, Dixon Liane, Wakeman Christopher J, Eglinton Tim W, Frizelle Frank A

机构信息

Colorectal Unit, Department of Surgery, Christchurch Hospital, Christchurch, New Zealand.

出版信息

ANZ J Surg. 2017 Dec;87(12):1011-1014. doi: 10.1111/ans.13501. Epub 2016 Apr 8.

Abstract

BACKGROUND

The management of diverticular disease and its complications are an increasing burden to the health system. The natural history of conservatively managed diverticular abscesses (Hinchey I and II) is poorly described and it remains open to debate whether subsequent sigmoid resection is indicated after conservative management. This observational study compares outcomes of patients treated with conservative management (antibiotics +/- percutaneous drainage) and surgery.

METHODS

All patients admitted at Christchurch Hospital with diverticulitis between 1 January 1998 and 31 December 2009 were recorded in a database. A retrospective analysis of patients with an abscess due to complicated diverticulitis was undertaken. Initial management, recurrence and subsequent surgery were recorded. The patients were followed until 1 January 2014.

RESULTS

Of 1044 patients with diverticulitis, 107 with diverticular abscess were included in this analysis. The median age was 66 ± 16 and 60 were male. All patients had sigmoid diverticulitis and were diagnosed with a computed tomography. The median abscess size was 4.2 ± 2.1 cm. During median follow-up of 110 months, the overall recurrence rate was 20% (21/107). Recurrence varied according to initial treatment; namely antibiotics (30%), percutaneous drainage plus antibiotics (27%) and surgery (5%) (P = 0.004). The median time to recurrence was 4 ± 11.7 months, and most recurrences were treated conservatively; four patients underwent delayed surgery.

CONCLUSION

Recurrence after diverticular abscess is higher after initial conservative treatment (antibiotics +/- percutaneous drainage) compared with surgery, however, patients with recurrent disease can be treated conservatively with similar good outcomes and few patients required further surgery.

摘要

背景

憩室病及其并发症的管理给卫生系统带来了日益沉重的负担。对于保守治疗的憩室脓肿(Hinchey I级和II级)的自然病程描述甚少,保守治疗后是否需要进行后续的乙状结肠切除术仍存在争议。这项观察性研究比较了接受保守治疗(抗生素+/-经皮引流)和手术治疗的患者的结局。

方法

1998年1月1日至2009年12月31日期间在克赖斯特彻奇医院因憩室炎入院的所有患者均记录在一个数据库中。对因复杂性憩室炎导致脓肿的患者进行回顾性分析。记录初始治疗、复发情况及后续手术情况。对患者进行随访直至2014年1月1日。

结果

在1044例憩室炎患者中,本分析纳入了107例憩室脓肿患者。中位年龄为66±16岁,男性60例。所有患者均为乙状结肠憩室炎,通过计算机断层扫描诊断。脓肿中位大小为4.2±2.1cm。在中位随访110个月期间,总体复发率为20%(21/107)。复发情况因初始治疗而异;即抗生素治疗(30%)、经皮引流加抗生素治疗(27%)和手术治疗(5%)(P=0.004)。复发的中位时间为4±11.7个月,大多数复发采用保守治疗;4例患者接受了延迟手术。

结论

与手术相比,憩室脓肿初始保守治疗(抗生素+/-经皮引流)后复发率更高,然而,复发性疾病患者可采用保守治疗,效果良好,很少有患者需要进一步手术。

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