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经皮引流结肠憩室脓肿:是否需要结肠切除术?

Percutaneous drainage of colonic diverticular abscess: is colon resection necessary?

机构信息

Division of Colon and Rectal Surgery, Department of Surgery, University of Minnesota, Minneapolis, Minnesota 55455, USA.

出版信息

Dis Colon Rectum. 2013 May;56(5):622-6. doi: 10.1097/DCR.0b013e31828545e3.

Abstract

BACKGROUND

Recurrent diverticulitis has been reported in up to 30% to 40% of patients who recover from an episode of colonic diverticular abscess, so elective interval resection is traditionally recommended.

OBJECTIVE

The aim of this study was to review the outcomes of patients who underwent percutaneous drainage of colonic diverticular abscess without subsequent operative intervention.

DESIGN

This was an observational study.

SETTINGS

This investigation was conducted at a tertiary care academic medical center and a single-hospital health system.

PATIENTS

Patients treated for symptomatic colonic diverticular abscess from 2002 through 2007 were included.

MAIN OUTCOME MEASURES

The primary outcomes measured were complications, recurrence, and colectomy-free survival.

RESULTS

Two hundred eighteen patients underwent percutaneous drainage of colonic diverticular abscesses. Thirty-two patients (15%) did not undergo subsequent colonic resection. Abscess location was pelvic (n = 9) and paracolic (n = 23), the mean abscess size was 4.2 cm, and the median duration of percutaneous drainage was 20 days. The comorbidities of this group of patients included severe cardiac disease (n = 16), immunodeficiency (n = 7), and severe pulmonary disease (n = 6). Freedom from recurrence at 7.4 years was 0.58 (95% CI 0.42-0.73). All recurrences were managed nonoperatively. Recurrence was significantly associated with an abscess size larger than 5 cm. Colectomy-free survival at 7.4 years was 0.17 (95% CI 0.13-0.21).

LIMITATIONS

This study was limited by its retrospective, nonexperimental design and short follow-up.

CONCLUSION

In selected patients, observation after percutaneous drainage of colonic diverticular abscess appears to be a safe and low-risk management option.

摘要

背景

据报道,在患有结肠憩室脓肿并康复的患者中,有 30%至 40%会出现复发性憩室炎,因此传统上建议进行择期间隔切除。

目的

本研究旨在回顾接受经皮结肠憩室脓肿引流而未行后续手术干预的患者的结局。

设计

这是一项观察性研究。

设置

该调查在一家三级保健学术医疗中心和一家单一医院医疗系统中进行。

患者

纳入了 2002 年至 2007 年间接受治疗的有症状结肠憩室脓肿患者。

主要观察指标

主要观察指标为并发症、复发和免于结肠切除术的生存情况。

结果

有 218 例患者接受了经皮结肠憩室脓肿引流。32 例(15%)患者未行随后的结肠切除术。脓肿位置为盆腔(n=9)和结肠旁(n=23),脓肿平均大小为 4.2cm,经皮引流中位数为 20 天。该组患者的合并症包括严重心脏病(n=16)、免疫缺陷(n=7)和严重肺部疾病(n=6)。7.4 年时无复发率为 0.58(95%CI 0.42-0.73)。所有复发均经非手术治疗处理。脓肿直径大于 5cm 与复发显著相关。7.4 年时免于结肠切除术的生存率为 0.17(95%CI 0.13-0.21)。

局限性

本研究受到其回顾性、非实验设计和随访时间短的限制。

结论

在选择的患者中,经皮引流结肠憩室脓肿后进行观察似乎是一种安全且低风险的治疗选择。

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