Catanese B, Valeri P, Lagana A, Curini L
F. Angelini Research Institute, Rome, Italy.
Biopharm Drug Dispos. 1989 Mar-Apr;10(2):225-8. doi: 10.1002/bdd.2510100211.
An aqueous solution of 0.15 per cent benzydamine hydrochloride, a non-steroidal anti-inflammatory drug, was applied to the rabbit eye. Following topical application to the cornea, the drug was soon detected in the aqueous fluid of the treated eye, whereas the plasma levels were negligible. The possibility that benzydamine can inhibit inflammatory processes in the eye without the risk of side-effects is discussed.
将一种非甾体抗炎药——0.15%盐酸苄达明的水溶液滴入兔眼。局部应用于角膜后，很快在用药眼的房水中检测到该药物，而血浆水平可忽略不计。本文讨论了苄达明能够抑制眼部炎症过程而无副作用风险的可能性。
